PRF for Treating Maxillary Gingival Recession

NCT ID: NCT05267015

Last Updated: 2022-03-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-03

Study Completion Date

2021-11-14

Brief Summary

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This is a split-mouth, randomized, controlled clinical trial that aims to evaluate the clinical efficacy of platelet-rich fibrin (PRF) membranes in conjunction with coronally advanced flap (CAF) in treating maxillary gingival recession defects.

Detailed Description

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Conditions

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Gingival Recession

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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coronally advanced flap with connective tissue graft

After randomization a subepithelial connective tissue graft along with coronally advanced flap is applied to one maxillary quadrant to cover the recession.

Group Type ACTIVE_COMPARATOR

Gingival coverage using coronally advanced flap and a connective tissue graft

Intervention Type PROCEDURE

A coronally advanced flap is applied for recession coverage in the maxilla in a split-mouth randomized trial using a subepithelial connective tissue graft

coronally advanced flap with platelet rich fibrin membranes

After randomization platelet rich fibrin membranes along with coronally advanced flap are applied to the other maxillary quadrant to cover the recession.

Group Type EXPERIMENTAL

Gingival coverage using coronally advanced flap and platelet rich fibrin membranes

Intervention Type PROCEDURE

A coronally advanced flap is applied for recession coverage in the maxilla in a split-mouth randomized trial using platelet rich fibrin membranes

Interventions

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Gingival coverage using coronally advanced flap and a connective tissue graft

A coronally advanced flap is applied for recession coverage in the maxilla in a split-mouth randomized trial using a subepithelial connective tissue graft

Intervention Type PROCEDURE

Gingival coverage using coronally advanced flap and platelet rich fibrin membranes

A coronally advanced flap is applied for recession coverage in the maxilla in a split-mouth randomized trial using platelet rich fibrin membranes

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Greater than 18 years old
* Bilateral Miller class I + II recession in the upper jaw

Exclusion Criteria

* Smokers
* Patients with systemic diseases that could interfere with the healing
* Patients undergoing bisphosphonate therap .Patients who previously received radiation therapy of the jaws.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Arab American University (Palestine)

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Abu-Ta'a

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mahmoud F Abu-Ta'a, Periodontist

Role: PRINCIPAL_INVESTIGATOR

Head of Department

Locations

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Arab American University

Ramallah, , Palestinian Territories

Site Status

Countries

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Palestinian Territories

References

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Abu-Ta'a M. Advanced Platelet-Rich Fibrin and Connective Tissue Graft for Treating Marginal Tissue Recessions: A Randomized, Controlled Split-Mouth Study. Cureus. 2023 Mar 4;15(3):e35761. doi: 10.7759/cureus.35761. eCollection 2023 Mar.

Reference Type DERIVED
PMID: 36879584 (View on PubMed)

Other Identifiers

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ArabAmericanU

Identifier Type: -

Identifier Source: org_study_id

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