Bilirubin Levels to Diagnose Appendicitis and Predict Appendiceal Perforation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

98 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-16

Study Completion Date

2025-03-12

Brief Summary

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The goal of this study is to learn if serum bilirubin levels can aid in the diagnosis of acute appendicitis and predict appendiceal perforation

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Detailed Description

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The study aims to assess hyperbilirubinemia: serum direct, indirect and total bilirubin to enhance the diagnostic accuracy of acute appendicitis. Also it aims to analyze different patient variables such as age, gender, duration of symptoms, leukocyte and neutrophil count, Alvarado score, presence of fever, nausea \& vomiting, peritonitis alongside serum total bilirubin level in patients with appendicitis and assess which variables can be taken as independent factors to predict appendiceal perforation.

Conditions

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Acute Appendicitis Appendicitis Perforated

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients of age group above 5 years with acute appendicitis undergoing appendectomy

Patients of age group above 5 years with acute appendicitis undergoing appendectomy, without acute or chronic liver diseases, acquired or congenital bilirary diseases, history of use of hepatotoxic drugs or diagnosis of appendicular lump

Non-interventional

Intervention Type OTHER

Non-interventional study

Interventions

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Non-interventional

Non-interventional study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients of age group above 5 years with acute appendicitis undergoing appendectomy with written informed consent.

Exclusion Criteria

* Patients with appendicular lump.
* Patients with acute and chronic liver diseases like acute hepatitis, hemolytic disease, Gilbert's syndrome, Dubin-Johnson syndrome, alcoholic liver disease.
* Acquired or Congenital Biliary Disease.
* History of Hepatotoxic drugs.

Minimum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No