Immediate Implant Placement With Deproteinized Bovine Bone vs Deproteinized Bovine Bone With HAM Gel

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-07

Study Completion Date

2025-08-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Statement of the problem: Immediate implant placement is faced with several problems. One of the most important is the jumping gap present after implant placement and whether it needs to be augmented or not.

Aim: The aim of this study is to compare the effect of xenograft to xenograft mixed with HAM gel for grafting of the jumping gap in immediate implant placement in the molar region.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Socket Evaluation System to Predict Labial Bone Formation Around Immediate Implants. A Retrospective Cone Beam Computed Tomography Analysis.

NCT06246253

Immediate Implant Placement

COMPLETED

Implant Placement in Mandibular Molar Xenograft Versus PRF

NCT03177356

Edentulous Alveolar Ridge

UNKNOWN NA

Investigate New Surgical Techniques to Improve Esthetics and Patient Satisfaction at Implant Sites

NCT04101552

Fractured Tooth

UNKNOWN NA

Immediate Implant Placement With Provisionalization Using Different Bone Grafts as a Space Filling Material in the Maxillary Esthetic Zone

NCT03741036

Dental Implant Failed

UNKNOWN NA

Alveolar Ridge and Soft Tissue Augmentation Using Graft From the Maxillary Tuberosity

NCT05670067

Immediate Implant Placement

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Aim: The aim of this study is to compare the effect of xenograft to xenograft mixed with HAM gel for grafting of the jumping gap in immediate implant placement in the molar region.

Materials and Methods: This parallel arm, randomized controlled clinical trial will involve systemically free patients with remaining roots or badly decayed teeth in the posterior region requiring implant placement. They will be randomly allocated to two equal groups. Group A (control group, n=12) will receive immediate implants (grafting with xenograft), and group B (test group, n=12) will receive immediate implants (grafting with xenograft\& HAM). After implant placement, buccal bone thickness (1ry outcome), bone density (2nd outcome) and implant stability will be assessed (2nd outcome). The parameters will be assessed at baseline, 6 and 12 months. Postoperative pain and swelling will be recorded daily by the patient for the 1st two weeks post surgically. Postoperative medication will be prescribed to the patient and postoperative instructions will be explained in detail. Follow-up will be performed to assess the parameters and to ensure performing proper oral hygiene. Data collected will be tabulated and statistically analyzed.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Badly Broken Down Vital Teeth

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

blinding of outcome assessors and participants will be achieved as the different outcomes will be assessed for all groups by assessors other than the researchers doing the procedures.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Xenograft

Gap distance grafting using xenograft.

Group Type ACTIVE_COMPARATOR

Xenograft

Intervention Type PROCEDURE

Gap distance grafting using xenograft

Xenograft mixed with HAM gel.

Gap distance grafting using xenograft mixed with HAM gel.

Group Type ACTIVE_COMPARATOR

Xenograft mixed with HAM gel.

Intervention Type PROCEDURE

Gap distance grafting using xenograft mixed with HAM gel.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Xenograft

Gap distance grafting using xenograft

Intervention Type PROCEDURE

Xenograft mixed with HAM gel.

Gap distance grafting using xenograft mixed with HAM gel.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients at least 18 years old, with non-restorable first and second molars indicated for immediate implant placement in both arches.
* Patient who are medically free patients (American Society of Anesthesiologists I; ASA I)
* Minimum remaining alveolar height of four to six millimeters distance from the apex of the socket to the floor of maxillary sinus for maxillary teeth and minimum remaining alveolar height of six millimeters distance from the apex of the socket to the inferior alveolar nerve for mandibular teeth.
* Minimum alveolar Bucco-palatal dimension of 7 mm.

Exclusion Criteria

* Patients with known systemic diseases which can affect normal bone formation or blood coagulation.
* Patients who are smokers.
* Presence of signs of active infection or pus formation.
* Absence or loss of buccal wall prior to implant placement.

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes