Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

NCT ID: NCT06899867

Last Updated: 2025-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-27

Study Completion Date

2025-11-01

Brief Summary

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Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery.

This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

Detailed Description

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Conditions

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Liver Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients undergoing liver transplantation at Croix-Rousse University Hospital, HCL, Lyon.

* Monitoring transesophageal echography, transpulmonary thermodilution
* Measuring cardiac index, preload dependence (end-expiratory test) at 4 steps of surgery
* Surgical anastomosis echography
* Demographic data, biological data, post operation data

Measure of cardiac index with thermodilution and transesophageal echocardiography

Intervention Type OTHER

At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution

Surgical anastomosis echography

Intervention Type OTHER

Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Interventions

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Measure of cardiac index with thermodilution and transesophageal echocardiography

At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution

Intervention Type OTHER

Surgical anastomosis echography

Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* liver transplantation
* adults

Exclusion Criteria

* \- Oesophageal varice ligation \< 14 days
* Mediastinal radiotherapy
* Femoral bypass
* Severe lower extremity artery disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Croix Rousse Hsopital

France, Lyon, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Pr Alice Blet

Role: CONTACT

Facility Contacts

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BLET Alice, MD,PhD

Role: primary

Other Identifiers

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24-5431

Identifier Type: -

Identifier Source: org_study_id

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