A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices: The Novel Cor-IS Technology Will Also be Evaluated
NCT ID: NCT06890013
Last Updated: 2025-07-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
100 participants
OBSERVATIONAL
2024-06-01
2026-11-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Observation group
Patients hospitalized due to acute coronary syndromes (STEMI, NSTEMI)
Observation group
Patients with acute coronary syndrome undergo endothelial function assessment using two methods (flow mediated dilatation of the brachial artery and Cor-Is technology) transthoracic echocardiogram and plasma biomarkers' measurement.
Interventions
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Observation group
Patients with acute coronary syndrome undergo endothelial function assessment using two methods (flow mediated dilatation of the brachial artery and Cor-Is technology) transthoracic echocardiogram and plasma biomarkers' measurement.
Eligibility Criteria
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Inclusion Criteria
2. Patients hospitalized due to acute coronary syndrome (STEMI, NSTEMI)
3. Capability of providing written informed consent
4. Patients able to comply with the follow-up schedule of the study
Exclusion Criteria
2. Patients with rare acute coronary syndrome types, such as spontaneous coronary artery dissection or Takotsubo syndrome
3. Patients with congenital heart disease
4. Age \> 85 years
5. Patients with end stage chronic kidney disease
6. Patients with active malignancy or autoimmune diseases which limit their survival
7. Patients with expected survival \< 1 year due to other reasons
8. Suboptimal echocardiographic windows
9. Inability to provide written consent
10. Inability to comply with the follow-up schedule of the study
11. Pregnancy
12. Use of intravenous drugs
18 Years
85 Years
ALL
No
Sponsors
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Aristotle University Of Thessaloniki
OTHER
Responsible Party
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Principal Investigators
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Christodoulos E. Papadopoulos, PhD
Role: PRINCIPAL_INVESTIGATOR
Aristotle University of Thessaloniki, Greece
Georgios Zormpas, MD
Role: PRINCIPAL_INVESTIGATOR
Aristotle University of Thessaloniki, Greece
Locations
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Ippokratio General Hospital
Thessaloniki, , Greece
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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198/31.5.2024
Identifier Type: -
Identifier Source: org_study_id
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