Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular Dysfunction

NCT ID: NCT02132585

Last Updated: 2014-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2014-05-31

Brief Summary

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Speckle tracking (STE) is a novel echocardiographic technique which permits calculation of myocardial velocities and deformation parameters such as strain and strain rate (SR). It is demonstrated that these parameters provide important insights into systolic and diastolic function, ischaemia, myocardial mechanics and many other pathophysiological processes of the heart. In this preliminary study, we investigated the role of STE in detection of early ventricular dysfunction in patients with Sjogren Syndrome, focusing on cardiorespiratory fitness.

Detailed Description

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Conditions

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Sjogren Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Sjogren

Sjogren Patients evaluated with Speckle tracking echocardiography

Speckle tracking echocardiography

Intervention Type PROCEDURE

Control

Controls Speckle tracking echocardiography

Speckle tracking echocardiography

Intervention Type PROCEDURE

Interventions

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Speckle tracking echocardiography

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of Sjogren Syndrome

Exclusion Criteria

* previous cardiovascular events
* unstable angina
* stroke
* diagnosis of heart failure
* incapacity to provide an informed consent
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Roma La Sapienza

OTHER

Sponsor Role lead

Responsible Party

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Gianturco Luigi

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Galeazzi IRCCS of Milan

Milan, Italy, Italy

Site Status

Sapienza University

Rome, , Italy

Site Status

Countries

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Italy

Other Identifiers

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Spk-001

Identifier Type: -

Identifier Source: org_study_id

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