The Diastolic Pressure Gradient for Patients With Acute Coronary Syndrome: Evaluation of Non Culprit Lesions

NCT ID: NCT01671631

Last Updated: 2012-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Study Classification

OBSERVATIONAL

Brief Summary

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The assessment of non-culprit stenoses is an important issue in ACS. Adenosine administration is currently required for functional evaluation of stenosis severity using the fractional flow reserve (FFR). An alternative adenosine-independent index of coronary stenosis, the instantaneous wave-free ratio (iFR), was recently introduced.

Aim of the present study will be to evaluate the trans-stenotic instantaneous wave-free pressure gradient (iFG), the instantaneous wave-free ratio (iFR) and the fractional flow reserve (FFR) in ACS patients.

Detailed Description

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Conditions

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Functional Evaluation of Non Culprit Lesions in ACS Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Acute Coronary Syndrome

Patients with Acute Coronary Syndrome and multivessel coronary artery disease undergoing functional evaluation of non-culprit lesions.

Measurement of intracoronary pressure

Intervention Type OTHER

Interventions

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Measurement of intracoronary pressure

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age 40 to 80 years
* recent Acute Coronary Syndrome
* indication for coronary angiography
* presence of at least one non-culprit lesion requiring functional evaluation with fractional flow reserve (FFR):

Exclusion Criteria

* Haemodynamically significant valvular disease
* controindication for Adenosin administration
* previous CABG on the index vessel
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Magna Graecia

OTHER

Sponsor Role lead

Responsible Party

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Ciro Indolfi

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cardiologia Interventistica UMG

Catanzaro, Calabria, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Ciro Indolfi, Prof

Role: CONTACT

Phone: +3909613647067

Email: [email protected]

Facility Contacts

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Ciro Indolfi, Prof.

Role: primary

Related Links

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http://www.cardiologia.unicz.it

Web site, Division of Cardiology at Magna graecia University

http://www.dsmc.unicz.it

Web site, Dipartimento di Scienze Mediche e Chirurgiche, Magna Graecia University

Other Identifiers

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FORECAST

Identifier Type: -

Identifier Source: org_study_id