Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

420 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-01

Study Completion Date

2027-03-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of blood transfusion or various interventions to increase hemoglobin levels on outcomes continue to be debated. The effects of hemoglobin levels in emergency surgery patients on the development of postoperative AKI have been investigated in a small number of studies in the literature, and clear results have not yet been reported. This study was designed to evaluate the effect of hemoglobin levels on the development of AKI after adjustment for known predictive factors.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Perioperative Myocardial and Renal Injury in Patients Undergoing Hepatic Resection

NCT06775158

Liver Neoplasm Kidney Injury, Acute Myocardial Injury After Non-Cardiac Surgery

COMPLETED

Haematologic Predictors and Clinical Outcome in Cardiac Surgery

NCT02653885

Cardiac Disease

COMPLETED

Femoral Blood Gas and Prediction of Postoperative Bleeding

NCT06285656

Postoperative Hemorrhage Blood Transfusion

NOT_YET_RECRUITING

Study on the Relationship of Arterial-venous Oxygen Difference and Postoperative Complications After Cardiac Surgery.

NCT05078086

Patient Blood Management Cardiac Surgery Transfusion

COMPLETED

Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection

NCT05331495

Aortic Dissection

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Acute kidney injury (AKI) is a common complication in patients undergoing major surgery and is associated with both short-term morbidity and mortality and long-term adverse outcomes including the development of Chronic Kidney Failure. Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of various interventions such as blood transfusion or increasing hemoglobin levels on outcomes continue to be debated. This prospective observational study was planned to evaluate the effect of hemoglobin levels before emergency surgery on the development of postoperative AKI.

Emergency operated patients will be divided into two groups as Group AKI and Group non-AKI according to the development of postoperative renal failure. Postoperative AKI diagnosis and severity will be evaluated according to serum creatinine and/or urine output according to KDIGO (Kidney Disease: Improving Global Outcomes criteria).

Demographic characteristics of the patients, preoperative complete blood count, blood biochemistry characteristics, hemodynamic variables, fluid replacement, blood and blood product replacements, surgical characteristics, development and severity of AKI in the postoperative period will be recorded and the effect of hemoglobin level on the development of AKI will be evaluated.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Emergency Surgery Acute Kidney Injury Hemoglobin

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group AKI

Postoperative renal failure

Observational

Intervention Type OTHER

Postoperative acute kidney injury and hemoglobin level relationship observation

Group non-AKI

Postoperative non renal failure

Observational

Intervention Type OTHER

Postoperative acute kidney injury and hemoglobin level relationship observation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Observational

Postoperative acute kidney injury and hemoglobin level relationship observation

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients undergoing emergency non-cardiac surgery

Exclusion Criteria

* Known renal failure
* Need for reoperation within 48 hours postoperatively
* Exit status within 48 hours postoperatively
* Known hematological disease
* Known kidney transplantation
* Urgent surgery planned due to urinary system related diseases
* Patients who did not accept to participate in the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No