The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

127 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-08-20

Study Completion Date

2017-12-01

Brief Summary

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Venoarterial CO2 difference(delta PCO2), lactate, central venous oxygen saturation(ScVO2) will be recorded in several steps in coronary artery bypass graft and valvular cardiac operations. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Detailed Description

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Preoperative creatinine values, demographic data, comorbidities will be recorded in ASA I-II elective coronary artery and valvular cardiac surgery patients. Intraoperative delta PCO2, lactate, ScVO2 will be recorded in several steps. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Conditions

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Cardiac Procedure Complication

Keywords

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tissue oxygenation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Transfused

Patients who have blood transfusion during cardiac surgery

Blood transfusion

Intervention Type BIOLOGICAL

The transfusion of erythrocyte suspension

Not-Transfused

Patients who don't have blood transfusion during cardiac surgery

No interventions assigned to this group

Interventions

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Blood transfusion

The transfusion of erythrocyte suspension

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Elective cardiac surgery, stable cardiac function

Exclusion Criteria

* Clinical signs of heart failure, symptomatic cerebral or peripheral failure, uncontrolled diabetes mellitus

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Büşra Tezcan

Specialist doctor

Responsibility Role PRINCIPAL_INVESTIGATOR