Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology

NCT ID: NCT06834958

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-01

Study Completion Date

2028-10-31

Brief Summary

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The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis

Detailed Description

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2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects:

1. Inclusion criteria:

patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal .
2. Exclusion criteria:

malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, …): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed

Conditions

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Acute Appendicitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient included who have acute appendicitis clinically and normal WBCS count

Appendectomy

Intervention Type PROCEDURE

Open surgery for appendix which is inflamed

Interventions

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Appendectomy

Open surgery for appendix which is inflamed

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Male or female patients é clinically diagnosed acute appendicitis with normal WBCS

Exclusion Criteria

* complicated AA (perforation, peri appendicular abscess or suspicion of a tumor.

2\_inflammatory bowel diseases 3\_inability to co-operate and give informed consent 4\_diffuse peritonitis 5\_Patients with serious comorbid conditions DM \& renal insufficiency, serum creatinine \> 150 μmol/l 6\_Pregnant \& lactating patient 7\_Patients with advanced malignancies \& pt on immunosuppressive drugs
Minimum Eligible Age

14 Days

Maximum Eligible Age

60 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Abdelrhman Kotb

Surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Assuit university

Asyut, , Egypt

Site Status

Countries

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Egypt

Related Links

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Other Identifiers

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Clinical diagnosis of acute ap

Identifier Type: -

Identifier Source: org_study_id

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