Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-01

Study Completion Date

2021-12-31

Brief Summary

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Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.

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Detailed Description

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Conditions

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Acute Appendicitis Acute Appendicitis With Rupture Acute Appendicitis Without Peritonitis Acute Appendicitis With Appendix Abscess Appendicitis; Perforation Appendicitis Perforated Appendicitis Acute

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

RCT

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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24 hour intravenous antibacterial therapy

S.Augmentin 1,2g x 3 i/v

Group Type ACTIVE_COMPARATOR

Oral versus intravenous administration of antibacterial treatment

Intervention Type OTHER

Mode of administration of antibacterial treatment

24 hour oral antibacterial therapy

T.Augmentin 1g x 3 p/o

Group Type EXPERIMENTAL

Oral versus intravenous administration of antibacterial treatment

Intervention Type OTHER

Mode of administration of antibacterial treatment

Interventions

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Oral versus intravenous administration of antibacterial treatment

Mode of administration of antibacterial treatment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patients diagnosed with acute appendicitis and are candidates for laparoscopic appendectomy.

Exclusion Criteria

Patients with compromised immune system (HIV, diabetes), ongoing or completed radio-chemotherapy in past 5 years, prosthetic heart valve, vascular prosthesis, pregnancy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes