Acute Appendicitis: The Influence of C-reactive Protein and Leucocytes on Clinical Decision-making

NCT ID: NCT02304653

Last Updated: 2015-05-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

226 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-02-28

Study Completion Date

2013-11-30

Brief Summary

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Aim: To investigate if the results of CRP and leucocytes had any positive or negative influence on the surgeon's decision-making when handling patients with suspected AA.

Detailed Description

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A prospective observational cohort study including patients (≥15 years of age) admitted on suspicion of AA. The surgeons were instructed to perform their physical examination and register whether they found the patient more or less than 50% likely to have AA. Thereafter, the surgeons had to assess the blood results and reevaluate their diagnosis. The surgeon's diagnosis before and after was compared to the final diagnosis defined by surgical findings or follow up. Gold standard was any degree of appendicitis on histology.

Conditions

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Acute Appendicitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Clinical descision making

Chage in diagnosis before and after the presentation of the reults of CRP and Leucocytes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Acutae abdominal pain Suspect for acute appendicites
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Danish Council for Independent Research

OTHER

Sponsor Role collaborator

Odense University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Niels Qvist

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Niels Qvist, Professor

Role: STUDY_DIRECTOR

Head of surgical eserach unit

Locations

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Odense University Hospital, surgical department A

Odense C, , Denmark

Site Status

Countries

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Denmark

References

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Tind S, Qvist N. Acute Appendicitis: A Weak Concordance Between Perioperative Diagnosis, Pathology and Peritoneal Fluid Cultivation. World J Surg. 2017 Jan;41(1):70-74. doi: 10.1007/s00268-016-3686-8.

Reference Type DERIVED
PMID: 27541029 (View on PubMed)

Tind S, Lassen AT, Zimmerman-Nielsen E, Qvist N. C-reactive protein and white blood cell count do not improve clinical decision-making in acute appendicitis. Dan Med J. 2015 Dec;62(12):A5167.

Reference Type DERIVED
PMID: 26621395 (View on PubMed)

Other Identifiers

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12-132020

Identifier Type: -

Identifier Source: org_study_id

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