Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

103 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-02-29

Study Completion Date

2008-08-31

Brief Summary

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The values of laboratory examinations which are useful for the diagnoses of acute appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR). Another laboratory value which has recently received considerable attention for the early diagnosis of bacterial infection and sepsis is pro-calcitonin (PCT). In recent studies it has been clearly shown that PCT is one of the most important biochemical indicators which closely correlates with the severity of inflammatory host response to microbial infections. Aim of this open, prospective study is therefore to investigate if PCT has an accurate diagnostic value for the diagnosis of acute appendicitis.

Detailed Description

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Conditions

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Appendicitis

Keywords

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Diagnostic Appendicitis Procalcitonin

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of appendicitis

Exclusion Criteria

* Antibiotic therapy
* Infection at other body sites
* Age \< 14 years
* Appendectomy in the medical history

Minimum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Michael Sand

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Benno Mann, PD Dr. med.

Role: STUDY_CHAIR

Department of General and Visceral Surgery, Augusta Krankenanstalt, Academic Teaching Hospital of the Ruhr-University Bochum

Michael Sand, Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Department of General and Visceral Surgery, Augusta Krankenanstalt, Academic Teaching Hospital of the Ruhr-University Bochum

Locations

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Department of General and Visceral Surgery, Augusta Krankenanstalt, Academic Teaching Hospital of the Ruhr-University Bochum, Germany

Bochum, , Germany

Site Status

Countries

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Germany

References

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Sand M, Trullen XV, Bechara FG, Pala XF, Sand D, Landgrafe G, Mann B. A prospective bicenter study investigating the diagnostic value of procalcitonin in patients with acute appendicitis. Eur Surg Res. 2009;43(3):291-7. doi: 10.1159/000232939. Epub 2009 Aug 7.

Reference Type RESULT

PMID: 19672084 (View on PubMed)

Other Identifiers

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PCT 01

Identifier Type: -

Identifier Source: org_study_id