3D Analysis of Soft Tissue Healing After Immediate Implant Placement Using PRF Vs HAM
NCT ID: NCT06834802
Last Updated: 2025-02-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
36 participants
INTERVENTIONAL
2025-01-07
2025-09-01
Brief Summary
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Aim: The aim of this study is to compare the effect of using HAM (Human amniotic membrane) and platelet rich fibrin (PRF) in soft tissue healing with immediate implant placement in the molar region.
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Detailed Description
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Materials and Methods: This parallel arm, randomized controlled clinical trial will involve systemically free patients with remaining roots or badly decayed teeth in molar sites region requiring implant placement. They will be randomly allocated to three equal groups. Group A (test group, n=12) will receive immediate implants (grafting with PRF), group B (test group, n=12) will receive immediate implants (grafting with HAM) and group c (test group, n=12) will receive immediate implants (no grafting). After implant placement, soft tissue healing (1ry outcome) and postoperative pain (2nd outcome) will be assessed. The parameters will be assessed at baseline, every day for the first week, day after day second week, once in third and fourth week. Postoperative pain and swelling will be recorded daily by the patient for the 1st two weeks post surgically. Postoperative medication will be prescribed to the patient and postoperative instructions will be explained in detail. Follow-up will be performed to assess the parameters and to ensure performing proper oral hygiene. Data collected will be tabulated and statistically analyzed.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Grafting with PRF
immediate implant will be placed and PRF membrane will be placed into the soft tissue. The PRF plug will be maintained in place with approximating sutures using 5-0 resorbable suture material.
PRF
PRF membrane will be used for soft tissue grafting around implant
Grafting using Human amniotic membrane (HAM)
immediate implant placement will be done and The HAM plug will be placed into the soft tissue.
Human amniotic membrane
Human amniotic membrane will be used for soft tissue grafting around implan
No Grafting
Immediate implant placement will be done and with no soft tissue grafting
No grafting
No soft tissue grafting around implant
Interventions
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PRF
PRF membrane will be used for soft tissue grafting around implant
Human amniotic membrane
Human amniotic membrane will be used for soft tissue grafting around implan
No grafting
No soft tissue grafting around implant
Eligibility Criteria
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Inclusion Criteria
2. Minimum remaining alveolar height of four to six millimeters distance from the apex of the socket to the floor of maxillary sinus for maxillary teeth and minimum remaining alveolar height of six millimeters distance from the apex of the socket to the inferior alveolar nerve for mandibular teeth.
3. Minimum alveolar Bucco-palatal dimension of 7 mm.
Exclusion Criteria
2. Patients who are smokers.
3. Presence of signs of active infection or pus formation.
4. Absence or loss of buccal wall prior to implant placement.
5. Bad oral hygiene
18 Years
60 Years
ALL
Yes
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Locations
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faculty of oral and dental medicine , Suez university
Cairo, Cairo Governorate, Egypt
Countries
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Other Identifiers
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3D soft tissue assessment
Identifier Type: -
Identifier Source: org_study_id
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