Comparative Factorial Study Design of Ultrasound Guided Wrist Block for Hand Surgery Comparing Effect of Bupivacane Alone and Bupivacane with Dexamethasone and Bupivacane with Dexametmiodine and Bupivacane with Dexamethasone and Dexametmiodine

NCT ID: NCT06826690

Last Updated: 2025-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-02

Study Completion Date

2025-09-10

Brief Summary

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Ultrasound guided wrist block comparing effect of bupivacane alone and bupivacane with dexamethasone and bupivacane with dexametmiodine and bupivacane with dexamethasone and dexametmiodine

Detailed Description

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Ultrasound guided wrist block comparing effect of bupivacane alone and bupivacane with dexamethasone and bupivacane with dexametmiodine and bupivacane with dexametmiodine and dexamethasone.

Taking medical and surgical history from patients. Taking base line data as heart rate and blood pressure and spo2. Measure duration of analgesia for post operative pain using NRS for 24 hours abd recording NRS at time interval of 2 , 4,6,12,24 hours post operative.

Any patient the NRS above 4 will receive 5 mg nalbufin . Recording patients satisfaction by a survey .

Conditions

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Hand Surgeries

Study Design

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Allocation Method

NA

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group 1: ultrasound guided wrist block with bupivacane alone

Group 1: ultrasound guided wrist block with bupivacane.025% .. 15 ml volume totally

Group Type ACTIVE_COMPARATOR

No interventions assigned to this group

Group2: ultrasound guided wrist block with bupivacane.25% and 8mg dexamethasone

Group 2: 40 patients receive ultrasound guided wrist block with 15 ml volume including bupivacane.25% and 8 mg dexamethasone

Group Type ACTIVE_COMPARATOR

No interventions assigned to this group

Group 3: ultrasound guided wrist block with bupivacane and dexametmiodine

Group 3: 40 patients receive ultrasound guided wrist block with 15 ml volume totally including bupivacane.25% and 50 mcg dexametmiodine

Group Type ACTIVE_COMPARATOR

No interventions assigned to this group

Group 4: ultrasound guided wrist block with bupivacane and dexametmiodine and dexamethasone

Group 4 : 40 patients receive ultrasound guided wrist block with 15 ml volume including bupivacane.25% and 8 mg dexamethasone and 50 mcg dexametmiodine

Group Type ACTIVE_COMPARATOR

No interventions assigned to this group

Interventions

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Group 1: ultrasound guided wrist block with bupivacane alone

Ultrasound guided wrist block with 15 ml volume of bupivacane.25%

Intervention Type PROCEDURE

Group 2 : ultrasound guided wrist block with bupivacane and dexamethasone

Group 2 : patients receive ultrasound guided wrist block with bupivacane.25% and 8 mg dexamethasone.. 15 ml volume totally

Intervention Type PROCEDURE

Group 3: ultrasound guided wrist block with bupivacane and dexametmiodine

Group 3 will receive ultrasound guided wrist block with bupivacane.25% and 50 mcg dexametmiodine... 15 ml volume totally

Intervention Type PROCEDURE

Group 4: patients will receive ultrasound guided wrist block with bupivacane and dexamethasone and dexametmiodine

Group 4 patients will receive ultrasound guided wrist block with bupivacan.25%e and 8 mg dexamethasone and 50 mcg dexametmiodine

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Patients more than or equal 18 years old and are ASA 1-3

Exclusion Criteria

* allergy to used medication
* pre exist neuropathy
* coagulapthy
* cognitive impairment
* refusal to participate
* Failed block and requiring general anesthesia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mahmoud Rafaat Mohamed

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Rafaat Mohamed

Resident doctor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Zaher Zaki Zaher, Specialist

Role: STUDY_DIRECTOR

Locations

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Aswan university hospital

Aswān, Aswan Governorate, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mahmoud RAFAAT Mohamed, Resident doctor

Role: CONTACT

201024289235

Other Identifiers

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963-9-24

Identifier Type: -

Identifier Source: org_study_id

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