Effect of Verapamil as an Adjuvant to Local Anaethetics in Supraclav Block for Hand Surgery
NCT ID: NCT06847620
Last Updated: 2025-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
32 participants
INTERVENTIONAL
2024-03-01
2024-10-15
Brief Summary
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Detailed Description
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Intraoperative Period On arrival of the patients to the operative room, electrocardiography, non-invasive blood pressure, and pulse oximetry will be applied. Baseline parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP), heart rate (HR), and oxygen saturation (SpO2) will be recorded. Intravenous (IV) line will be inserted and IV lactated Ringer will be started.
The block will be performed using a portable ultrasound system (sonosite M-turbo USA) with linear high-frequency transducer (12HZ) to get the sonographic anatomy of brachial plexus in the transverse and longitudinal planes.
Under aseptic conditions, the ultrasound probe will be situated parallel to the clavicle in the supraclavicular area to show the plexus as a "bunch of grapes" or as having a "honeycomb" appearance. The block will be done with a short beveled echogenic needle 5 cm, 22 G for optimal control and visibility. The predetermined volume of 22 ml will be injected around the brachial plexus after negative aspiration to avoid inadvertent intravascular injection keeping in mind adequate block of lower trunk. Distension of brachial plexus sheath will be regarded as an indication of successful block "Donut sign". A massage for 5 min will be applied to aid an equal volume distribution.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
SINGLE
Study Groups
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• Group A (the control group)
group A: will receive 20 ml of plain bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml of normal saline.
Supraclavicular Brachial Plexus Block
The block will be performed using a portable ultrasound system (sonosite M-turbo USA) with linear high-frequency transducer (12HZ) to get the sonographic anatomy of brachial plexus in the transverse and longitudinal planes.
Bupivacaine 0.25% 20ml alone
will receive 20 ml of plain bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml of normal saline.
Group B
Group B : will receive 20 ml of bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml verapamil (equivalent to 5 mg)
Supraclavicular Brachial Plexus Block
The block will be performed using a portable ultrasound system (sonosite M-turbo USA) with linear high-frequency transducer (12HZ) to get the sonographic anatomy of brachial plexus in the transverse and longitudinal planes.
bupivacaine 0.25% And verapamil
will receive 20 ml of bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml verapamil (equivalent to 5 mg
Interventions
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Supraclavicular Brachial Plexus Block
The block will be performed using a portable ultrasound system (sonosite M-turbo USA) with linear high-frequency transducer (12HZ) to get the sonographic anatomy of brachial plexus in the transverse and longitudinal planes.
Bupivacaine 0.25% 20ml alone
will receive 20 ml of plain bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml of normal saline.
bupivacaine 0.25% And verapamil
will receive 20 ml of bupivacaine 0.25% (equivalent to 50 mg) plus 2 ml verapamil (equivalent to 5 mg
Eligibility Criteria
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Inclusion Criteria
* Patients with ASA I / II
* patients undergoing hand surgeries
Exclusion Criteria
* Skin infection at the injection site.
* Contraindications to regional anaesthesia as bleeding disorders
* Allergy to bupivacaine or other drugs involved in the study.
* Uncooperative patients.
* BMI \>35
* Patients taking medications for psychiatric illness
21 Years
70 Years
ALL
Yes
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Locations
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Ain Shams University Hospitals
Cairo, , Egypt
Countries
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Other Identifiers
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FMASU MS165/2024
Identifier Type: -
Identifier Source: org_study_id
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