The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery
NCT ID: NCT06806410
Last Updated: 2025-02-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE4
120 participants
INTERVENTIONAL
2023-05-01
2025-01-30
Brief Summary
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patients consented to this study will be randomized into three groups: 1) will receive an ultrasound guided nerve block with local anesthesia only, 2) will receive an ultrasound guided nerve block with local anesthesia and a steroid dexamethasone, 3) will receive an ultrasound guided nerve block with liposomal bupivacaine.
our study team will make phone calls after surgery to the patient to determine how long the block lasted for, and how many opioid pain pills were taken up to 3 days after surgery.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Control Arm: local anesthesia only in ultrasound guided supraclavicular nerve block
ultrasound guided supraclavicular nerve blocks are typically performed with the use of local anesthesia only
No interventions assigned to this group
Study Arm: local anesthesia with perineural dexamethasone
dexamethasone is a potent steroid that when provided in ultrasound guided nerve blocks can extend the duration of the nerve block.
Dexamethasone
dexamethasone injected in perineural area can extend the regional nerve block
Study Arm: liposomal bupivacaine
our study team would like to determine how use of liposomal bupivacaine in supraclavicular nerve blocks can lengthen the duration of the nerve block, and how it may affect the number of opioid pills used after surgery up until postoperative day three.
Liposomal bupivacaine (LB)
our study team wishes to determine effect of liposomal bupivacaine in regional nerve blocks for surgery of the upper extremity (finger, hand, wrist, elbow)
Interventions
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Liposomal bupivacaine (LB)
our study team wishes to determine effect of liposomal bupivacaine in regional nerve blocks for surgery of the upper extremity (finger, hand, wrist, elbow)
Dexamethasone
dexamethasone injected in perineural area can extend the regional nerve block
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* patients greater than 18 years of age, able to provide written consent for surgery and study
Exclusion Criteria
* patients with known allergies to local anesthetics
* patients with severe liver disease
* patients with a condition known as methemoglobinemia
18 Years
ALL
Yes
Sponsors
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St. Luke's Hospital, Pennsylvania
OTHER
Responsible Party
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Principal Investigators
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Anna Ng-Pellegrino, MD
Role: PRINCIPAL_INVESTIGATOR
St. Luke's Hospital and Health Network, Pennsylvania
Locations
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St. Luke's University Health Network
Bethlehem, Pennsylvania, United States
Countries
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Other Identifiers
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SLIR2023-34
Identifier Type: -
Identifier Source: org_study_id
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