Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
75 participants
INTERVENTIONAL
2023-04-28
2026-04-27
Brief Summary
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The objectives are to: 1) analyze how tDCS modulates neuronal activity, 2) evaluate persistent effects in follow-up assessments, and 3) predict patient outcomes. Studies on human subjects will be complemented by research in a mouse model of stroke to: 1) identify the molecular mechanisms underlying tDCS effects on functional recovery, 2) establish correlations among functional, molecular, and connectivity indices, and 3) assess the efficacy of biomimetic nanoparticles in targeting injured brain tissue to reduce inflammation, enhance neuronal plasticity, and support functional recovery.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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tDCS+standard rehabilitation
tDCS
Transcranial direct current stimulation
tDCS sham+standard rehabilitation
tDCS
Transcranial direct current stimulation
standard rehabilitation
No interventions assigned to this group
Interventions
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tDCS
Transcranial direct current stimulation
Eligibility Criteria
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Inclusion Criteria
* First ischemic stroke occurring 3-30 days after onset
* Residual upper limb function
* Ability to provide informed consent and understand instructions
Exclusion Criteria
* Presence of additional neurological diseases
* Significant comorbidities
* History of intracerebral hemorrhage
* Severe neglect
* Contraindications to tDCS
18 Years
90 Years
ALL
No
Sponsors
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IRCCS San Raffaele Roma
OTHER
Responsible Party
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Locations
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Casa di cura San Raffaele Pisana
Rome, Rome, Italy
Countries
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Other Identifiers
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RP 22/24
Identifier Type: -
Identifier Source: org_study_id
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