Reflexology and Mulligan Mobilization for Knee Osteoarthritis

NCT ID: NCT06815016

Last Updated: 2025-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-20

Study Completion Date

2026-04-20

Brief Summary

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to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees

Detailed Description

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Knee osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. Treatment by reflexology stimulation increases blood flow to the associated organ or body part. On the other hand, the nerve impulse theory claims that reflexology stimulation boosts nervous connection to the conforming body parts. Regarding to the energy theory; organs and body parts are connected through electromagnetic fields and that these pathways are blocked in states of disease. Finally, lactic acid theory pointed that lactic acid accumulates on the soles of the feet in the form of crystals which promotes free circulation, so reduces regular flow .The effects of foot reflexology on improving physical complains of KOA. Therefore, this study was conducted to evaluate the effectiveness of reflexology foot massage on pain intensity and physical functional abilities among patients with Knee Osteoarthritis.

Mulligan's Mobilization with Movement (MWM) advocates therapist-applied accessory gliding force combined with active movement The goal of MWM is to achieve immediate pain relief possibly by regulation of the non-opioid pain sensory pathways and by correction of micro positional faults. These positional faults may result from changes in the shape of articular surfaces, cartilage thickness, fiber orientation in the capsule-ligamentous complex, and the direction of musculo-tendinous pull, causing altered mechanics in the osteoarthritic knees.

Conditions

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Knee Osteoarthritis Knee Osteoarthritis (Knee OA)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Reflexology and conventional

treatment all patient with knee osteoarthritis three times per week

Group Type EXPERIMENTAL

reflexology and conventional

Intervention Type OTHER

Reflexology as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

mulligan mobilization and conventional

treatment all patient with knee osteoarthritis three times per week

Group Type EXPERIMENTAL

mulligan mobilization and conventional

Intervention Type OTHER

Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Reflexology ,mulligan mobilization and conventional

treatment all patient with knee osteoarthritis three times per week

Group Type EXPERIMENTAL

Reflexology ,mulligan mobilization and conventional

Intervention Type OTHER

Reflexology is a systematic practice in which applying some pressure to any particular points on the feet and hands give impacts on the health of related parts of the body as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) Mulligan's Mobilization with Movement (MWM) apply accessory gliding force combined with active movement as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise)

mulligan mobilization and conventional

Intervention Type OTHER

Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Conventional methods

treatment all patient with knee osteoarthritis three times per week

Group Type EXPERIMENTAL

Conventional treatment

Intervention Type OTHER

Conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Interventions

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Reflexology ,mulligan mobilization and conventional

Reflexology is a systematic practice in which applying some pressure to any particular points on the feet and hands give impacts on the health of related parts of the body as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) Mulligan's Mobilization with Movement (MWM) apply accessory gliding force combined with active movement as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise)

Intervention Type OTHER

reflexology and conventional

Reflexology as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Intervention Type OTHER

mulligan mobilization and conventional

Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Intervention Type OTHER

Conventional treatment

Conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Age greater than or equal to 40 years.
2. Body Mass Index ≤30 kg/m².
3. All participants have Calcium Deficiency
4. Osteoarthritis in mild and moderate stage not in the acute stage
5. The subjects were chosen from both genders

Exclusion Criteria

1. Deep Vein Thrombosis
2. Fractures
3. Gangrena Patient
4. Osteopenic Patient
5. Lactating or pregnant women
6. Cancer
7. Neurological conditions.
8. Patients with injury including; (lesions, sprain, open wounds, foot ulcer and or burn of the lower extremities), hemorrhage, epilepsy, irregular heartbeat.
9. Vascular (Anticoagulant Therapy, Aortic Aneurysm)
10. Neurological Deficits (multilevel PIVD, Cervical Myelopathy)
11. Psychological Disorders.

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Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Rania Ahmed Nassar

demonstrator physical therapy

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Noran A Elbehary, Professor of physical Therapy

Role: PRINCIPAL_INVESTIGATOR

basic science department, faculty of physical therapy cairo university

Mariam O Grase, lecturer physical therapy

Role: PRINCIPAL_INVESTIGATOR

basic science department, faculty of physical therapy cairo university

Locations

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Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Rania a nassar, master

Role: CONTACT

01010618797

Facility Contacts

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Rania a nassar, master

Role: primary

01010618797

References

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Bakir E, Baglama SS. The Effect of Foot Reflexology and Knee Massage With Black Cumin Seed Oil on Knee Osteoarthritis Symptoms. Holist Nurs Pract. 2024 Dec 5. doi: 10.1097/HNP.0000000000000714. Online ahead of print.

Reference Type BACKGROUND
PMID: 39642267 (View on PubMed)

Bhagat M, Neelapala YVR, Gangavelli R. Immediate effects of Mulligan's techniques on pain and functional mobility in individuals with knee osteoarthritis: A randomized control trial. Physiother Res Int. 2020 Jan;25(1):e1812. doi: 10.1002/pri.1812. Epub 2019 Sep 10.

Reference Type BACKGROUND
PMID: 31502354 (View on PubMed)

Other Identifiers

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P.T.REC/012/005479

Identifier Type: -

Identifier Source: org_study_id

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