Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

NCT ID: NCT06810375

Last Updated: 2025-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-01

Study Completion Date

2029-02-28

Brief Summary

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This clinical trial compares efficacy in postoperative pain management in thoracic surgery between erector spinae block versus liposomal bupivacaine injections.

Detailed Description

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Conditions

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Lung Cancers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Preoperative Erector Spinae Block (ESB)(Bupivacaine)(Marcaine®)

Group Type ACTIVE_COMPARATOR

Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

Intervention Type DRUG

preoperative erector spinae block with bupivacaine (Marcaine®)

Intercostal nerve block

Intervention Type DRUG

intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)

Intraoperative Intercostal Nerve Block (INB)(Liposomal Bupivacaine)(Exparel®)

Group Type ACTIVE_COMPARATOR

Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

Intervention Type DRUG

preoperative erector spinae block with bupivacaine (Marcaine®)

Intercostal nerve block

Intervention Type DRUG

intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)

Interventions

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Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

preoperative erector spinae block with bupivacaine (Marcaine®)

Intervention Type DRUG

Intercostal nerve block

intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Video assisted pulmonary resection, pleurodesis or decortication

Exclusion Criteria

* Allergy to local anesthetics
* Patient undergoing bilateral surgery
* Surgery is emergent as deemed by the principal investigator
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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George Washington University

OTHER

Sponsor Role lead

Responsible Party

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Akhil Patel

MD, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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The George Washington University Hospital

Washington D.C., District of Columbia, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Eduard Shaykhinurov, MS

Role: CONTACT

2022038960

Facility Contacts

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Eduard Shaykhinurov

Role: primary

2022038960

Other Identifiers

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NCR246143

Identifier Type: -

Identifier Source: org_study_id

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