Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
NCT ID: NCT05038007
Last Updated: 2021-09-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE2
50 participants
INTERVENTIONAL
2021-09-15
2022-05-31
Brief Summary
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Detailed Description
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At Aalborg University Hospital, intercostal blockades with bupivacaine is used as standard pain treatment for patients undergoing VATS. Adding adjuvants to the blockades may prolong the effect.
The aim of this study is to examine if intercostal nerve blockades with liposomal bupivacaine improves postoperative pain management compared to intercostal nerve blockades with bupivacaine hydrochloride.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Control
Bupivacaine Hydrochloride in perioperative intercostal blockades
Bupivacaine Hydrochloride
As prior described
Intervention
Liposomal bupivacaine in perioperative intercostal blockades
Liposomal bupivacaine
As prior described
Interventions
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Liposomal bupivacaine
As prior described
Bupivacaine Hydrochloride
As prior described
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients undergoing VATS as a part of either examination or treatment of lung cancer
Exclusion Criteria
* Patients with known chronic pain in the thorax which have been persisting for at least six months before the day of surgery.
* Pregnant and nursing women.
* Patients with hypersensitivity / allergy / Intolerance to dexamethasone or bupivacaine.
* Patients receiving a planned preoperative epidural blockade during their stay.
* Patients converted to open surgery.
18 Years
ALL
No
Sponsors
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Jannie Bisgaard Stæhr
OTHER
Responsible Party
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Jannie Bisgaard Stæhr
Principal Investigator
Principal Investigators
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Jannie Bisgaard, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Aalborg University Hospital, department of Anaesthesiology
Locations
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Aalborg University Hospital
Aalborg, Region of Northern Jutland, Denmark
Countries
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Central Contacts
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Other Identifiers
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AAUH-VATS-01
Identifier Type: -
Identifier Source: org_study_id
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