Serratus Plain Block Versus Paravertebral Block Versus Serratus Plain Block and Paravertebral Block for Postoperative Pain Following Thoracoscopic Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

155 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-02

Study Completion Date

2023-02-22

Brief Summary

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Acute and chronic postoperative pain remains a major concern following thoracoscopic surgery. Firstly because pain constitutes a serious concern for patients after surgery, and secondarily because an ineffective control of pain may lead to postoperative morbidity, especially in lung cancer surgery.

To date, several procedures have been described but the best modality of locoregional analgesia for thoracoscopic surgery has not been assessed yet. The main objective of this study is to evaluate efficiency of several validated approaches for preoperative locoregional analgesia, comparing serratus plain block versus paravertebral block versus serratus plain block and paravertebral block for postoperative pain following thoracoscopic surgery.

To this end, the investigators will conduct an interventional prospective monocentric, double blind, compared and randomized study. Previously to thoracoscopic surgery, patients will be randomized in one of the three following arms: serratus plain block, paravertebral block or serratus plain block and paravertebral block combined.

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Detailed Description

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Conditions

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Anesthesia, Local Pain, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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serratus loco-regional anesthesia

patient who underwent thoracoscopic surgery will be assigned to serratus plane bloc (Ropivacaine 2 mg/mL, 40 mL) and paravertebral placebo bloc (saline, 20 mL)

Group Type EXPERIMENTAL

loco-regional anesthesia serratus plane bloc (Ropivacaine 2 mg/mL, 40 mL) and paravertebral placebo bloc (saline, 20 mL)

Intervention Type DRUG

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia

paravertebral bloc Loco-regional anesthesia

patient who underwent thoracoscopic surgery will be assigned to paravertebral bloc (Ropivacaine 4 mg/mL, 20 mL) and serratus plane placebo bloc (saline, 40 mL)

Group Type EXPERIMENTAL

Loco-regional anesthesia : paravertebral bloc (Ropivacaine 4 mg/mL, 20 mL) and serratus plane placebo bloc (saline, 40 mL)

Intervention Type DRUG

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia.

serratus and paravertebral bloc Loco-regional anesthesia

patient who underwent thoracoscopic surgery will be assigned to serratus plane bloc (Ropivacaine 1,3 mg/mL, 40 mL) and paravertebral bloc (Ropivacaine 1,3 mg/mL, 20 mL)

Group Type EXPERIMENTAL

Loco-regional anesthesia : serratus plane bloc (Ropivacaine 1,3 mg/mL, 40 mL) and paravertebral bloc (Ropivacaine 1,3 mg/mL, 20 mL)

Intervention Type DRUG

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia.

Interventions

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loco-regional anesthesia serratus plane bloc (Ropivacaine 2 mg/mL, 40 mL) and paravertebral placebo bloc (saline, 20 mL)

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia

Intervention Type DRUG

Loco-regional anesthesia : paravertebral bloc (Ropivacaine 4 mg/mL, 20 mL) and serratus plane placebo bloc (saline, 40 mL)

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia.

Intervention Type DRUG

Loco-regional anesthesia : serratus plane bloc (Ropivacaine 1,3 mg/mL, 40 mL) and paravertebral bloc (Ropivacaine 1,3 mg/mL, 20 mL)

Each patient who underwent thoracoscopic surgery will be assigned to one procedure of Loco-regional anesthesia.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* adult patient over18 years old
* without guardianship
* video-assisted thoracoscopic surgery with 3 trocars
* No cons-indications to loco-regional anesthesia (allergy, skin condition)

Exclusion Criteria

* patient under 18 years old
* patient under guardianship
* pregnant
* rejection of consent
* rejection of loco-regional anesthesia
* chronic pain antecedents under morphine medication
* pain assessment impossible

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No