Fluid Responsiveness and Venous Congestion Evolution During Volume Expansion
NCT ID: NCT06772038
Last Updated: 2025-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
64 participants
OBSERVATIONAL
2025-01-05
2025-07-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Fluid Responder
Patients with an aumentation of cardiac index\>= 15% after a fluid challenge
No interventions assigned to this group
Fluid Non-responder
Patients without an aumentation of cardiac index\>= 15% after a fluid challenge
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Hospitalized in the intensive care unit (ICU)
* Hemodynamic monitoring in place, with a pulse wave contour analysis- derived estimation of cardiac output (either calibrated or uncalibrated)
* Decision made by clinicians to perform volume expansion through intravenous infusion of crystalloid fluid
Exclusion Criteria
* Refusal to participate by relatives of the patient or the patient himself
18 Years
99 Years
ALL
No
Sponsors
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First Affiliated Hospital, Sun Yat-Sen University
OTHER
Longgang District People's Hospital of Shenzhen
OTHER
Bicetre Hospital
OTHER
Responsible Party
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Xavier Monnet
Professor Xavier Monnet, MD, PHD
Locations
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First affiliated Hospital , Sun Yat-sen University
Guangzhou, Guangdong, China
Longgang Central Hospital of Shenzhen
Shenzhen, Guangdong, China
Bicetre Hospital
Paris, Val-de-Marne, France
Countries
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Central Contacts
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Facility Contacts
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Xavier Monnet, PHD, MD
Role: backup
Xiang SI, MD
Role: backup
References
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Munoz F, Born P, Bruna M, Ulloa R, Gonzalez C, Philp V, Mondaca R, Blanco JP, Valenzuela ED, Retamal J, Miralles F, Wendel-Garcia PD, Ospina-Tascon GA, Castro R, Rola P, Bakker J, Hernandez G, Kattan E. Coexistence of a fluid responsive state and venous congestion signals in critically ill patients: a multicenter observational proof-of-concept study. Crit Care. 2024 Feb 19;28(1):52. doi: 10.1186/s13054-024-04834-1.
Monnet X, Shi R, Teboul JL. Prediction of fluid responsiveness. What's new? Ann Intensive Care. 2022 May 28;12(1):46. doi: 10.1186/s13613-022-01022-8.
Messina A, Calabro L, Pugliese L, Lulja A, Sopuch A, Rosalba D, Morenghi E, Hernandez G, Monnet X, Cecconi M. Fluid challenge in critically ill patients receiving haemodynamic monitoring: a systematic review and comparison of two decades. Crit Care. 2022 Jun 21;26(1):186. doi: 10.1186/s13054-022-04056-3.
Monnet X, Malbrain MLNG, Pinsky MR. The prediction of fluid responsiveness. Intensive Care Med. 2023 Jan;49(1):83-86. doi: 10.1007/s00134-022-06900-0. Epub 2022 Nov 3. No abstract available.
Joseph A, Petit M, Vignon P, Vieillard-Baron A. Fluid responsiveness and venous congestion: unraveling the nuances of fluid status. Crit Care. 2024 Apr 26;28(1):140. doi: 10.1186/s13054-024-04930-2. No abstract available.
Other Identifiers
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2022-A00580-43
Identifier Type: -
Identifier Source: org_study_id
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