Comparison of the Beverage Hydration Index of Different Solutions

NCT ID: NCT06733532

Last Updated: 2025-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

29 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-21

Study Completion Date

2025-03-21

Brief Summary

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The present study will assess the effects of two different hydration solutions compared to water on hydration measures. It will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance. Additionally, hydration status will be assessed with mood and digestive health questionnaires and blood pressure urine electrolyte concentrations, specific gravity, and osmolality determinations. The two oral rehydration solutions (Berry Propel Fitness Water and Essentia Hydroboost Raspberry Pomegranate) will be compared to the control (Smart Water). The purpose is to assess whether the changes in beverage composition improve the BHI above water alone for both treatments, with an hypothesized greater improvement in BHI observed with the Essentia Hydroboost Raspberry Pomegranate, due to the addition of carbohydrate.

Detailed Description

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The present study will assess the effects of two different hydration solutions compared to water on hydration measures. It will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance. Additionally, hydration status will be assessed with mood and digestive health questionnaires and blood pressure urine electrolyte concentrations, specific gravity, and osmolality determinations. The two oral rehydration solutions (Berry Propel Fitness Water and Essentia Hydroboost Raspberry Pomegranate) will be compared to the control (Smart Water). The purpose is to assess whether the changes in beverage composition improve the BHI above water alone for both treatments, with an hypothesized greater improvement in BHI observed with the Essentia Hydroboost Raspberry Pomegranate, due to the addition of carbohydrate.

Conditions

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Hydration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

semi-blinded
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants
treatments labeled A-C. Subjects will be provided the beverage in plastic cups without product labels

Study Groups

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Propel, Essentia, Smart

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type EXPERIMENTAL

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Propel, Smart, Essentia

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type EXPERIMENTAL

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Essentia, Smart, Propel

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type EXPERIMENTAL

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Essentia, Propel, Smart

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type ACTIVE_COMPARATOR

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Smart, Essentia, Propel

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type EXPERIMENTAL

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Smart, Propel, Essentia

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will consume the assigned treatment (one treatment per visit in order state in arm title) and additional experimental measurements will be collected.

Group Type EXPERIMENTAL

Berry Propel Fitness Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Essentia Hydroboost Raspberry Pomegranate

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Smart Water

Intervention Type DIETARY_SUPPLEMENT

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Interventions

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Berry Propel Fitness Water

Subject will consume 1 Liter of commercially available Berry Propel Fitness Water at a rate of 250 milliliters per 7.5 minutes

Intervention Type DIETARY_SUPPLEMENT

Essentia Hydroboost Raspberry Pomegranate

Subject will consume 1 Liter of commercially available Essentia Hydroboost Raspberry Pomegranate at a rate of 250 milliliters per 7.5 minutes

Intervention Type DIETARY_SUPPLEMENT

Smart Water

Subject will consume 1 Liter of commercially available Smart Water at a rate of 250 milliliters per 7.5 minutes.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* body mass index (BMI) \<35 kg/m2 (not morbidly obese)
* Cannot have a sensitivity or be allergic to any components of the study product they will be excluded.
* non-tobacco user
* cannot be following a specialized dietary pattern that may alter findings (e.g., low carbohydrate/ketogenic diet, carnivore diet, intermittent fasting etc.)
* willing to replicate the same dietary intake/activity (exercise) level for each day before a lab visit excluding screening
* Will consume a minimum of 2 liters (women) or 2.5 liters (men) of water per day, on each day prior to experimental lab visits (excluding screening)
* Will arrive to lab for visits euhydrated (USG 1.005-1.020)
* Will not consume alcohol-containing beverages within 24 hours of testing
* Will not consume caffeine-containing beverages within 12 hours of testing
* can fast (consume water/treatments only) for 15 hours (10 hours prior to lab visits not including screening)
* avoid strenuous activity for 24 hours prior to study visits excluding screening
* Will not have a history or presence of a clinically relevant (that required or requires treatment) cardiac, renal, hepatic, endocrine (including diabetes mellitus), pulmonary, biliary, gastrointestinal, pancreatic, or neurologic disorder (reviewed by Nurse practitioner)
* Will not have other conditions that is likely to alter fluid balance or be negatively affected by changing electrolyte levels/hydration status (as determined by Nurse practitioner)
* Is not consuming any medication which may alter fluid retention/electrolyte levels such as sodium-glucose co-transporter 2 (SGLT2) inhibitor (for type 2 diabetes), laxatives, diuretics, Apremilast, chemotherapy, or lithium. (Medications will be reviewed by Nurse practitioner)
* Will not consume nutritional supplements, performance enhancing drugs, and/or non-steroidal anti-inflammatory drugs within 7 days of study visits excluding screening.
* cannot be enrolled in another clinical study within 30 days of the first study visit
* without active infection or illness of any kind
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Memphis

OTHER

Sponsor Role lead

Responsible Party

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Richard Bloomer

Dean of the College of Health Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Richard J Bloomer, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Memphis

Locations

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Center for Nutraceutical and Dietary Supplement Research

Memphis, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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PRO-FY2024-372

Identifier Type: -

Identifier Source: org_study_id

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