Raspberry Ketone Intake Upregulates Circulating FGF21 and Induces Energy Expenditure in Humans

NCT ID: NCT06681597

Last Updated: 2024-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-10

Study Completion Date

2024-06-01

Brief Summary

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To investigate the molecular mechanism of raspberry ketone on regulating obesity, the investigators studied the effect of raspberry ketone intake on FGF21 in plasma.

The age of the volunteers were 18-60 years old, both male and female, without diabetes, hypertension and other diseases.

After ingestion of raspberry ketone (500mg), 2ml of blood was collected at 0 hours, 3 hours and 6 hours , and the FGF21 content in plasma was measured using a commercial reagent kit.

In addition, the investigators also studied the effect of raspberry ketone intake on energy metabolism 0 hours, 0.5 hours, 3 hours and 6 hours after consuming raspberry ketone (500mg).

Detailed Description

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Conditions

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Obesity Diabetes NAFLD (Nonalcoholic Fatty Liver Disease)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Human administrated with raspberry ketone

Group Type EXPERIMENTAL

Raspberry ketone

Intervention Type DIETARY_SUPPLEMENT

Human consumed 500mg of raspberry ketone

Human administrated with placebo

Group Type EXPERIMENTAL

Raspberry ketone

Intervention Type DIETARY_SUPPLEMENT

Human consumed 500mg of raspberry ketone

Interventions

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Raspberry ketone

Human consumed 500mg of raspberry ketone

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

No drugs were taken before the human study

Exclusion Criteria

Patients with hypertension
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nanchang University

OTHER

Sponsor Role lead

Responsible Party

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Ting Luo

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Nanchang University

Nanchang, Jiangxi, China

Site Status

Countries

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China

References

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Lopez HL, Ziegenfuss TN, Hofheins JE, Habowski SM, Arent SM, Weir JP, Ferrando AA. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr. 2013 Apr 19;10(1):22. doi: 10.1186/1550-2783-10-22.

Reference Type BACKGROUND
PMID: 23601452 (View on PubMed)

Other Identifiers

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I-MRER [2023] No. 68

Identifier Type: -

Identifier Source: org_study_id

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