Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries

NCT ID: NCT06658418

Last Updated: 2024-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE1

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-01

Study Completion Date

2026-12-01

Brief Summary

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To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries

Detailed Description

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Conditions

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Analgesia, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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dexmedetomidine combined with bupivacaine

use for Dexmedetomidine and bupivacain for erector spinae plane block

Group Type ACTIVE_COMPARATOR

Erector Spinae Plane Block

Intervention Type PROCEDURE

dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.

dexamethasone combined with bupivacaine

use of dexamethasone combined with bupivacaine for erector spinae plane block

Group Type EXPERIMENTAL

Erector Spinae Plane Block

Intervention Type PROCEDURE

dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.

Interventions

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Erector Spinae Plane Block

dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Age :18 years old and older. Patients undergoing open abdominal surgery.

Exclusion Criteria

1. Patient refusal
2. known sensitivity or contraindication to any of study drugs
3. contraindications for local anesthesia
4. Patients with local infection at site of puncture
5. uncooperative patients
6. history of psychological disorders or chronic pain and significant liver or renal disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Loay Gamal

OTHER

Sponsor Role lead

Responsible Party

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Loay Gamal

LGamal

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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loay GAMAL loay Gamal, master

Role: CONTACT

+201017675686

References

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Gottschalk A, Durieux ME, Nemergut EC. Intraoperative methadone improves postoperative pain control in patients undergoing complex spine surgery. Anesth Analg. 2011 Jan;112(1):218-23. doi: 10.1213/ANE.0b013e3181d8a095. Epub 2010 Apr 24.

Reference Type BACKGROUND
PMID: 20418538 (View on PubMed)

Other Identifiers

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erector spinae plane block

Identifier Type: -

Identifier Source: org_study_id

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