Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth
NCT ID: NCT06631885
Last Updated: 2024-10-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
20 participants
INTERVENTIONAL
2024-10-11
2025-04-11
Brief Summary
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Detailed Description
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Twenty individuals with necrotic, immature permanent anterior teeth will be recruited. They will be randomly assigned into two groups according to the received intervention: control group and test group.
pain will be evaluated as a primary outcome at 24 hours and one week post-intervention using numerical rating scale (NRS). In addition, the root development in terms of change in root length and apical foramen diameter and periapical bone healing will be evaluated as secondary outcomes using cone beam tomography.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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control group: using AAE protocol
revascularization using blood clot according to the standardized protocol of the American association of endodontics
regenerative endodontic procedure using blood clot according to AAE
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using AAE protocol
test group
diode laser will be used to activate photosensitized nano chitosan 2% for canal disinfection instead of NaOCl in the first visit of revascularization protocol
regenerative endodontic procedure using photo activated nanochitosan 2%
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using photosensitized nanochitosan for root canal disinfection
Interventions
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regenerative endodontic procedure using blood clot according to AAE
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using AAE protocol
regenerative endodontic procedure using photo activated nanochitosan 2%
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using photosensitized nanochitosan for root canal disinfection
Eligibility Criteria
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Inclusion Criteria
* Teeth where pulp space are not needed for post and core.
* A restorable tooth.
* Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
* Patients who will agree to the consent and will commit to follow-up period.
Exclusion Criteria
* Teeth with root fractures, internal or external root resorption.
* Teeth with mature fully developed root with closed apex
* Patients with any systemic disease that may affect predictable outcome
ALL
No
Sponsors
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Minia University
OTHER
Responsible Party
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Mohammed abdelmawla mohammed
assisstant lecturer of endodontics
Central Contacts
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Other Identifiers
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(586/2022)
Identifier Type: -
Identifier Source: org_study_id
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