A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

NCT ID: NCT06782087

Last Updated: 2025-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

PHASE1

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-15

Study Completion Date

2025-10-30

Brief Summary

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The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.

The discoloration of teeth might be intrinsic, extrinsic, or combined. A variety of commercial bleaching agents is available. The most common substances used are carbamide peroxide or hydrogen peroxide or a mixture of sodium perborate and hydrogen peroxide.

Detailed Description

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The aim of the study is to assess the effectiveness of two different in-office bleaching materials carbamide peroxide alone and carbamide peroxide with Chitosan nanoparticles Using diode laser as an activator Regarding tooth whitening and color stability 1 Day , 1 weeks, 1 month after treatment using Vita easy shade.

Conditions

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Tooth Discoloration

Study Design

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Allocation Method

NA

Intervention Model

SEQUENTIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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peroxides and sodium perborate and 980nm diode laser.

peroxides and sodium perborate + 980nm diode laser.

Group Type OTHER

nano chitosan

Intervention Type DRUG

nano chitosan

Interventions

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nano chitosan

nano chitosan

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* discolored crown, non-vital or endodontically treated upper central and lateral incisors
* previous endodontic treatment performed two or more years earlier.

Exclusion Criteria

* caries on upper central and lateral incisors, inadequate fillings, and progressive periodontal disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Misr University for Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Silvia Sabry

lecturer of conservative dentidtry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Manal abd el baky A dr, phd

Role: STUDY_DIRECTOR

Lecturer in conservative surgery departement

Locations

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Misr University for science and technology

Giza, Egypt, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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2022/0037

Identifier Type: -

Identifier Source: org_study_id

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