Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors

NCT ID: NCT05522270

Last Updated: 2022-08-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-01

Study Completion Date

2023-07-01

Brief Summary

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Regenerative endodontic procedures (REPs) are the most recent proposal to manage immature permanent teeth with necrotic pulps. So in this study, the investigator will evaluate the clinical and radiographical revitalization success in necrotic young permanent anterior teeth of participants by using Concentrated Growth Factor versus Platelet-Rich Fibrin

Detailed Description

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has been entered

Conditions

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Necrotic Pulp

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

parallel assignment
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
double (participant,outcomes Assessor)

Study Groups

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revitalization by concentrated growth factor

modified platelet concentrate

Group Type EXPERIMENTAL

revitalization by concentrated growth factor

Intervention Type PROCEDURE

modified platelet concentrate

revitalization by platelet rich fibrin

platelet concentrate

Group Type ACTIVE_COMPARATOR

revitalization by concentrated growth factor

Intervention Type PROCEDURE

modified platelet concentrate

Interventions

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revitalization by concentrated growth factor

modified platelet concentrate

Intervention Type PROCEDURE

Other Intervention Names

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revitalization by platelet rich fibrin

Eligibility Criteria

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Inclusion Criteria

* Healthy patients with immature permanent incisors
* Presence of clinical signs and symptoms of necrosis or chronic apical periodontitis. The chronic apical periodontitis signs and symptoms include little discomfort with intermittent episodes of pus discharge through the sinus tract.

Exclusion Criteria

1\. Abnormal tooth mobility.

* Positive history of allergic reaction, systemic diseases, severe emotional or behavioral problems.
* Unrestorable teeth
* Abnormal tooth mobility
* Children with systemic, severe behavioral, or emotional problems
Minimum Eligible Age

6 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ahmad Elheeny

OTHER

Sponsor Role lead

Responsible Party

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Ahmad Elheeny

clinical professor

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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ghada tony, doctora

Role: CONTACT

Phone: 01117902713

Email: [email protected]

Other Identifiers

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320

Identifier Type: -

Identifier Source: org_study_id