Perceptual Influences From Smoking Cannabis: an Experimental Study

NCT ID: NCT06588582

Last Updated: 2025-06-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

166 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-17

Study Completion Date

2029-07-31

Brief Summary

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The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and heart rate.

We expect that participants will be in this research study for approximately one week. The total amount of time that participants will spend completing study tasks will be about 2.5 hours across two separate in-person visits.

Detailed Description

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Conditions

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Cannabis Use Stress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Cold Water

Group Type EXPERIMENTAL

Water Temperature Variation - CW

Intervention Type OTHER

Participants are assigned to cold water temperature and are video recorded.

Warm Water

Group Type PLACEBO_COMPARATOR

Water Temperature Variation - WW

Intervention Type OTHER

Participants are assigned to warm water temperature.

Interventions

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Water Temperature Variation - WW

Participants are assigned to warm water temperature.

Intervention Type OTHER

Water Temperature Variation - CW

Participants are assigned to cold water temperature and are video recorded.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 21-65 years of age
* Endorsement of at least some use of cannabis for coping purposes (\>1 on CMMQ)
* Regularly use flower cannabis products (i.e., ≥1x/week in the last 6 months)
* Proficient in English language
* At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month)

Exclusion Criteria

* Diagnosis or use of medications for substance use or psychotic disorders
* Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs
* Females cannot be pregnant or trying to become pregnant or nursing mothers
* Not able to provide informed consent
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

University of Colorado, Boulder

OTHER

Sponsor Role lead

Responsible Party

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Carillon Skrzynski

Research Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Colorado at Boulder

Boulder, Colorado, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Carillon Skrzynski, PhD

Role: CONTACT

(734)788-2961

Facility Contacts

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Carillon Skrzynski, PhD

Role: primary

(734)788-2961

Other Identifiers

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1K01DA058152-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

23-03-0215

Identifier Type: -

Identifier Source: org_study_id

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