Lumbosacral Erector Spinae Plane Block Versus Psoas Muscle Compartment With Sciatic Nerve Block for Anesthesia for Unilateral Lower Limb Operations in Critically Ill Patients

NCT ID: NCT06580704

Last Updated: 2025-04-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 130 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-08-31
• Study Completion Date: 2025-03-26

Brief Summary

This study aims to compare lumbosacral erector spinae plane block and psoas muscle compartment with sciatic nerve block in unilateral lower limb operations in critically ill patients.

Detailed Description

The lower limb surgeries are associated with acute postoperative pain and require long-term analgesia. Regional anesthesia is often used to prevent postoperative pain. Ultrasound-guided regional anesthetic approaches provide a simple intraoperative pathway that lowers pain scores with less impact on the respiratory or cardiovascular system.

Psoas compartment block (PCB) is a peripheral regional technique of anesthesia, which provides a block of the main components of the lumbar plexus - the femoral, lateral cutaneous nerve of the femur and sciatic nerve. In combination with the sciatic nerve block, the psoas compartment block provides effective anesthesia of the entire lower extremity, with better hemodynamic stability.

The erector Spinae plane block (ESPB) is a novel regional block technique primarily introduced in 2016 for managing severe neuropathic pain.

Conditions

Lumbosacral; Erector Spinae Plane Block; Psoas Muscle Compartment Block; Sciatic Nerve Block; Anesthesia; Unilateral; Lower Limb; Critically Ill Patients

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Lumbosacral Erector Spinae Plane Block

Patients will receive ultrasound-guided lumbosacral erector spinae plane block.

Group Type: EXPERIMENTAL

Lumbosacral Erector Spinae Plane Block

Intervention Type: DRUG

Patients will receive ultrasound-guided lumbosacral erector spinae plane block.

Psoas Muscle Compartment With Sciatic Nerve Block

Patients will receive ultrasound-guided psoas muscle compartment with sciatic nerve block.

Group Type: EXPERIMENTAL

Psoas Muscle Compartment With Sciatic Nerve Block

Intervention Type: DRUG

Patients will receive ultrasound-guided psoas muscle compartment with sciatic nerve block.

Interventions

Lumbosacral Erector Spinae Plane Block

Patients will receive ultrasound-guided lumbosacral erector spinae plane block.

Intervention Type: DRUG

Psoas Muscle Compartment With Sciatic Nerve Block

Patients will receive ultrasound-guided psoas muscle compartment with sciatic nerve block.

Intervention Type: DRUG

Eligibility Criteria

Exclusion Criteria

• History of allergy to local anesthetics.
• Bleeding tendency.
• Coagulopathy.
• Anticoagulant therapy.
• Pre-existing psychological, neurologic, and spinal cord diseases.
• Previous back surgery.
• Infection or mass at the site of the block.
• Chronic analgesic therapy.
• Severe cardiac or renal diseases.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Tanta University

Tanta, El-Gharbia, Egypt

Countries

Egypt

Other Identifiers

36264PR761/7/24

Identifier Type: -

Identifier Source: org_study_id