Pericapsular Nerve Group and Lumbar Erector Spinae Plane Blocks for Geriatrics Undergoing Total Hip Arthroplasty

NCT ID: NCT06904703

Last Updated: 2025-04-01

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 120 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-12-01
• Study Completion Date: 2026-11-01

Brief Summary

This study will be conducted to evaluate the effect of pericapsular nerve group and erector spinae plane block as adjuvants to general anesthesia in geriatrics undergoing total hip arthroplasty.

Detailed Description

Total hip arthroplasty is one of the most common major orthopedic procedures to improve a patient's functional status and quality of life. Total hip arthroplasty is one of the most cost-effective and consistently successful surgeries performed in orthopedics and can be associated with significant postoperative pain.

General anesthesia may be considered more versatile and suitable for patients with complex medical histories or those who cannot tolerate spinal anesthesia. However, older patients undergoing hip fracture surgery under general anesthesia may experience a higher risk of postoperative delirium, prolonged sedation, and respiratory complications. Moreover, delayed mobilization is possible, leading to a higher incidence of complications such as deep vein thrombosis and pressure sores.

The target nerves of the hip joint arise from the lumbar plexus (L1-L4), the lumbosacral trunk of the sacral plexus (L4-L5), and the sacral spinal nerves (S1-S4) (7). The femoral nerve, obturator nerve, and the accessory obturator nerve supply the anterior capsule of the hip; the sciatic nerve and the nerve to the quadratus femoris mostly supply the articular branches to the posterior capsule of the hip joint The erector spinae plane block is a novel inter-fascial plane block targets the dorsal and ventral rami of the spinal nerves, is a newer regional anesthetic technique that can be used to provide analgesia for a variety of surgical procedures or to manage acute or chronic pain. This block can potentially provide analgesia to the posterior pelvis potentially safer alternative to epidural or paravertebral techniques, areas often involved in hip fracture pain.

The pericapsular nerve group block targets the articular branches of the femoral and obturator nerves near the hip joint capsule. By blocking these nerves, the pericapsular nerve group block effectively provides analgesia to the hip joint, particular tissues, and proximal femur.

Conditions

Pericapsular Nerve; Lumbar Erector Spinae Plane Blocks; Geriatrics; Total Hip Arthroplasty; General Anesthesia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

General anesthesia group

Patients will receive general anesthesia.

Group Type: EXPERIMENTAL

General anesthesia

Intervention Type: DRUG

Patients will receive general anesthesia.

Erector spinae plane block group

Patients will receive general anesthesia and erector spinae plane block.

Group Type: EXPERIMENTAL

Bupivacaine 0.5%

Intervention Type: DRUG

Patients will receive general anesthesia and erector spinae plane block.

Pericapsular nerve block group

Patients will receive general anesthesia and erector spinae plane block with pericapsular nerve block.

Group Type: EXPERIMENTAL

Bupivacaine 0.5%

Intervention Type: DRUG

Patients will receive general anesthesia and erector spinae plane block with pericapsular nerve block.

Interventions

General anesthesia

Patients will receive general anesthesia.

Intervention Type: DRUG

Bupivacaine 0.5%

Patients will receive general anesthesia and erector spinae plane block.

Intervention Type: DRUG

Bupivacaine 0.5%

Patients will receive general anesthesia and erector spinae plane block with pericapsular nerve block.

Intervention Type: DRUG

Other Intervention Names

Erector spinae plane block; Pericapsular nerve block

Eligibility Criteria

Inclusion Criteria

• Aged >75 years.
• Both sexes.
• American Society of Anesthesiologists (ASA) classification I-III.
• Undergoing total hip arthroplasty under general anesthesia.

Exclusion Criteria

• Patient refusal.
• Body mass index (BMI) > 30 kg/m2.
• Allergy to local anesthesia drugs.
• Infection at the site of intervention.
• Coagulopathies.
• Preexisting advanced diseases of the kidney or liver.

• Minimum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mai El-saieed Abdelghaffar Hamada

Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Management Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Faculty of Medicine

Tanta, , Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Mai El Hamada, MSc

Role: CONTACT

drmai7amada93@gmail.com

00201285851295

Facility Contacts

Mai El Hamada, MSc

Role: primary

drmai7amada93@gmail.com

00201285851295

Other Identifiers

36265MD311/11/24

Identifier Type: -

Identifier Source: org_study_id