Functional Yogurt Consumption and Its Effects on the Lipid Profile of Healthy Subjects

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-22

Study Completion Date

2024-05-07

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study was to assess the effect of the daily intake of yogurts enhanced with Sacha Inchi oil and hybrid palm tree oil on human plasma lipids related to cardiovascular risk factors

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effectiveness of Sacha Inchi Supplementation on Postprandial Inflammation

NCT02886169

Cardiovascular Diseases

COMPLETED NA

Intervention With n3 LC-PUFA-supplemented Yogurt

NCT01244048

Moderate Hypertriacylglycerolemic Subjects

COMPLETED NA

Enriched Yogurts With Soluble Fibre or Vegetable Protein on Satiety

NCT03625245

Overweight

COMPLETED NA

Repetitive Lipid Intake and Food Intake

NCT03901157

Satiation Overweight and Obesity Satiety Response

UNKNOWN NA

The Effect of Dairy and Non-dairy Breakfasts on Satiety and Post-meal Glycemia in Healthy Older Adults

NCT02607007

Diabetes Obesity

COMPLETED PHASE1/PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

After being recruited and signing a written informed consent about the study and potential risks, the participants were randomized and assigned in a double-blind manner to one of three intervention groups (control yogurt, sacha inchi oil yogurt, or hybrid palm tree oil yogurt; consumption 1 bottle of 200ml per day for 90 days.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cardiovascular Diseases Apolipoproteins Food Preferences Low-density-lipoprotein-type HDL Triglycerides Functional Food

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A pilot randomized; double-blind, parallel-controlled pragmatic trial was performed

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Forty-seven subjects were randomized and assigned to one of the three intervention groups supplemented daily with 200g of: Sacha Inchi Oil (SIO)-containing yogurt (Group-A), Hybrid palm oil (HPO)-containing yogurt (Group-B), and plain yogurt (Group-C).

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control yogurt

Participants consumed a 200 g bottle of plain Yogurt with 3.5% unreplaced fat orally, daily, for 90 days

Group Type PLACEBO_COMPARATOR

Control yogurt

Intervention Type OTHER

Conventional full-fat yogurt

Sacha inchi oil yogurt

Participants consumed a 200 g bottle of Yogurt with 3.5% replacement of dairy fat for Sacha inchi oil, orally, daily, for 90 days

Group Type EXPERIMENTAL

Sacha inchi oil yogurt

Intervention Type OTHER

Sacha inchi oil was incorporated into a nonfat yogurt acting as a source of linolenic acid

Hybrid palm oil yogurt

Participants consumed a 200 g bottle of Yogurt with 3.5% replacement of dairy fat for Hybrid Palm Oil, daily, for 90 days

Group Type EXPERIMENTAL

Hybrid palm oil yogurt

Intervention Type OTHER

Interspecific hybrid palm oil was incorporated into a nonfat yogurt as a source of bioactive compounds

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Sacha inchi oil yogurt

Sacha inchi oil was incorporated into a nonfat yogurt acting as a source of linolenic acid

Intervention Type OTHER

Hybrid palm oil yogurt

Interspecific hybrid palm oil was incorporated into a nonfat yogurt as a source of bioactive compounds

Intervention Type OTHER

Control yogurt

Conventional full-fat yogurt

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Normal total cholesterol (≤200mg/dl) levels
* Have a yogurt consumption habit of at least three times a week
* Maximum level of moderate physical activity
* Body mass index (BMI) of ≤29.9kg/m2
* Serum triacylglycerols below 400mg/dl

Exclusion Criteria

* Presence of chronic disease (Arterial hypertension, Diabetes Mellitus, among others)
* A history of illicit drug use and/or chronic alcohol use, active smoking
* A well-established allergy to red palm olein and/or milk and its derivatives
* Consumption of nutritional supplements (antioxidants, omega 3, fiber, phytosterols)
* Pregnancy or lactation
* Having menopause
* High consumption of nuts, flaxseed, chia, and sesame seeds

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes