Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-26

Study Completion Date

2026-07-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Background:

People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use.

Objective:

To see if Motion Reset software can reduce cybersickness in people using VR.

Eligibility:

Healthy adults aged 18 to 60 years.

Design:

Participants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers.

The study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups:

Group 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.

Group 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.

Group 3 will have no VR experience.

Participants will complete 2 questionnaires about their experiences in the first part of the study.

For the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort.

After playing the game, participants will complete 12 questionnaires about their experience....

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Cybersickness in Different Multisensory Conditions in Virtual Reality

NCT05534880

Cybersickness Reduced Sensation

COMPLETED NA

2-dimensional Versus 3-dimensional Virtual Reality Game Training in BPPV

NCT05021939

Vertigo

COMPLETED NA

Impact of Different Types of Virtual Reality Games on Motion Sickness and Ocular in Adults: A Pilot Study

NCT06354309

Amblyopia Motion Sickness Dry Eye

COMPLETED NA

Dose of Vestibular Rehabilitation for Vestibular Hypofunction

NCT04851184

Vestibular Disorder

TERMINATED NA

The Use of Virtual Reality for the Treatment of Visual Vertigo.

NCT03020654

Treatment of Visual Vertigo

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Study Description:

This study involves investigation of a virtual reality (VR) experience intended to prevent cybersickness (similar to motion sickness and eye strain) from use of virtual reality equipment. Participants will be randomly assigned to one of three arms: active intervention, placebo (a similar VR experience that does not engage sensory systems purported to underlie efficacy), or a notreatment control. Following the intervention, participants will play a VRbased game used in previous research to slowly induce moderate levels of cybersickness in some individuals. During play, we will assess self-reported feelings of discomfort. Participants will be allowed to stop playing at any time or will be asked to stop playing if discomfort reaches a certain threshold. Self-report data will be collected prior to and following the intervention.

Objectives:

Primary Objective: Evaluate efficacy of an approach for prevention of cybersickness symptoms when using virtual reality.

Secondary Objectives: Investigate individual difference factors associated with efficacy; assess mechanisms involved in treatment efficacy

Endpoints:

Primary Endpoint: Self-reported cybersickness symptoms on the Simulator Sickness Questionnaire

Secondary Endpoints: Self-reported cybersickness and duration of stimulus game play. Investigate individual difference factors associated with efficacy; assess mechanisms involved in treatment efficacy

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy Volunteers Virtual Reality

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Intervention: Motion Reset

Participate in virtual reality activities

Group Type EXPERIMENTAL

Motion Reset

Intervention Type BEHAVIORAL

virtual reality-based experiential, sensory intervention

No intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Placebo experience

Participate in virtual reality activities

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type BEHAVIORAL

virtual reality-based experiential, sensory experience without intervention

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Motion Reset

virtual reality-based experiential, sensory intervention

Intervention Type BEHAVIORAL

Placebo

virtual reality-based experiential, sensory experience without intervention

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Aged 18-60
* Ability to read, speak, and write in English
* Normal or corrected-to-normal hearing
* Normal vision or corrected-to-normal without use of glasses. Contact lenses for corrective purposes are acceptable.

Ability to read, speak and write in English is a requirement because the VR-based study materials and assessment are only available in English and several of the key questionnaires for the study are not validated in other languages.

Exclusion Criteria

An individual who meets any of the following criteria will be excluded from participation in this study:

* Reporting motion sickness propensity of 0, 9 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants).
* Reporting a history of photo-sensitive seizure disorders, vestibular disorders and/or other conditions that may make participants prone to nausea, dizziness, vertigo, ataxia, or incoordination.
* Known pregnancy
* Reporting current use of medication or supplements that inhibit nausea, e.g., Zofran/ondansetron, Phenergan/promethazine

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No