Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery

NCT ID: NCT06505499

Last Updated: 2025-01-10

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 51 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-03-06
• Study Completion Date: 2024-09-30

Brief Summary

Instrumented three dimensional gait analysis (3DGA) permits to record spatial, temporal, kinetics, kinematics and electromyographic (EMG) parameters in order to understand gait impairment in children and teenagers with cerebral palsy (CP). Nowadays, single-event multilevel surgery in subjects with CP cannot be performed without 3DGA. However, interpretation of multiple and interdependent data remains complex for the clinician. To address this issue, gait statistical index have been developed to give a single measure of the quality of the gait pattern. Among actual index, the Gait Profile Score (GPS), developed by Baker et al (2009), measure the deviation of kinematics parameters from a controlled dataset. The GPS can be divided in nine Gait Variable Score (GVS), corresponding to major lower limb joints: the MAP (Movement Analysis Profile). Many studies have reported the interest of the GPS to analysis gait of subjects with CP: good inter-session reliability, predictor of postoperative kinematic improvement, minimal clinical threshold calculated at 1.6°, significant relationship with clinical data (joint contractures), and sensibility to change after a single-event multilevel surgery.

Conditions

Cerebral Palsy; Gait Disorders in Children

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

EXPERIMENTAL GROUP

Children and teenagers with CP with an instrumented gait analysis performed since 2019.

Gait Profile Score

Intervention Type: OTHER

Gait Profile Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009).

Gait Visual Score

Intervention Type: OTHER

Gait Visual Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009)

Interventions

Gait Profile Score

Gait Profile Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009).

Intervention Type: OTHER

Gait Visual Score

Gait Visual Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009)

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Etiology of cerebral palsy
• Unilateral, bilateral, triplegic or quadriplegic forms of cerebral palsy.
• 6 to 18 years old
• GMFCS (Gross Motor Function Classification System) I to III
• Instrumented gait analysis of the laboratory of St-Etienne
• Absence of botulinum toxin injection or serial casting in the three months after a first instrumented gait analysis.

Exclusion Criteria

• Etiology others than cerebral palsy as defined classically (ex: ischemic infarcts in a child older than two years).
• Previous surgery in lower-limb.

• Minimum Eligible Age: 6 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Clément BOULARD, physiotherapist

Role: PRINCIPAL_INVESTIGATOR

CHU de Saint-Etienne

Locations

Chu de Saint Etienne

Saint-Etienne, , France

Countries

France

Other Identifiers

IRBN402024/CHUSTE

Identifier Type: -

Identifier Source: org_study_id