Association Between Iron Reserves and Perioperative Neurocognitive Disorders

NCT ID: NCT06502912

Last Updated: 2024-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

12984 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2021-12-31

Brief Summary

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Iron metabolism disorder have been identified as the pivotal contributor in the pathogenesis and progression of perioperative neurocognitive disorders. However, the association between iron reserves and perioperative neurocognitive disorders risk remains elusive. This retrospective cohort study aimed to explore the impact of preoperative serum ferritin levels on the risk of postoperative delirium in elderly patients undergoing non-neurosurgical and non-cardiac procedures.

Detailed Description

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Conditions

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Perioperative Neurocognitive Disorders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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elderly patients (aged ≥ 65 years)

elderly patients undergoing non-neurosurgical and non-cardiac procedures

no intervention

Intervention Type OTHER

no intervention

Interventions

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no intervention

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Geriatric surgical patients ≥65 years old

Exclusion Criteria

* preoperative use of antipsychotics
* diagnosis or history description of preoperative cognitive disorders including dementia and Parkinson's
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Weidong Mi

Director (Cheif expert of National key research and development program of China 2018YFC2001900)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Weidong Mi, PhD

Role: STUDY_CHAIR

Chinese PLA General Hospital

Other Identifiers

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PLAGH-AOC-R02

Identifier Type: -

Identifier Source: org_study_id

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