Rehydration Efficiency During Ad-libitum Fluid Intake

NCT ID: NCT06414291

Last Updated: 2025-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-21

Study Completion Date

2024-12-03

Brief Summary

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It is well established that rehydration with a carbohydrate-electrolyte solution is more effective in comparison to plain water. This is primarily based on the sodium-glucose co transporter, based on which the world health organization has based its oral rehydration solution recommendations. Also, rehydration with a solution that includes sodium and glucose plasma osmolality should not drop as much as it happens during rehydration with water. As a result, we should have higher fluid intake due to higher thirst perception and lower urinary output due to higher levels of vasopressin.

The present study aims to examine the effectiveness of a electrolyte-glucose drink on rehydration following exercise-induced dehydration.

Detailed Description

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Conditions

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Dehydration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants
non labeled bottles

Study Groups

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Water

Rehydration with low mineral content bottle water

Group Type PLACEBO_COMPARATOR

Plain Water

Intervention Type OTHER

Plain water without calories, sweetener, or electolytes

Carbohydrate Electrolyte solution

Drink with 22 grams of carbohydrate, 1020 milligrams of sodium, and 760 milligrams of potassium per liter. Hydration multiplier liquid IV

Group Type EXPERIMENTAL

Liquid IV Hydration Multiplier

Intervention Type OTHER

Drink with 22 grams of carbohydrate, 1020 milligrams of sodium, and 760 milligrams of potassium per liter. Hydration multiplier liquid IV

Low Sugar electrolyte solution

10 grams of carbohydrate, 1060 milligrams of sodium, and 760 milligrams of potassium per liter. Sugar free Liquid IV

Group Type EXPERIMENTAL

Liquid IV Sugar Free

Intervention Type OTHER

10 grams of carbohydrate, 1060 milligrams of sodium, and 760 milligrams of potassium per liter. Sugar free Liquid IV

Interventions

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Plain Water

Plain water without calories, sweetener, or electolytes

Intervention Type OTHER

Liquid IV Hydration Multiplier

Drink with 22 grams of carbohydrate, 1020 milligrams of sodium, and 760 milligrams of potassium per liter. Hydration multiplier liquid IV

Intervention Type OTHER

Liquid IV Sugar Free

10 grams of carbohydrate, 1060 milligrams of sodium, and 760 milligrams of potassium per liter. Sugar free Liquid IV

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18-60 years
* Training at least 2 times per week
* stable weight for the last 2 months (fluctuation less than 5 pounds)

Exclusion Criteria

* Night shifting work
* Thyroid medication
* Bariatric surgery
* Cardiovascular disease
* Renal disease
* Hepatic disease
* Participating in another study at the same time
* Bodyweight over 110 pounds
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Arizona State University

OTHER

Sponsor Role lead

Responsible Party

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Stavros Kavouras

Professor & Assistant Dean

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Interdisciplinary Science and Technology Building 8

Phoenix, Arizona, United States

Site Status

Countries

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United States

Other Identifiers

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FP00039672

Identifier Type: -

Identifier Source: org_study_id

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