Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study
NCT ID: NCT06405919
Last Updated: 2024-05-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
160 participants
OBSERVATIONAL
2017-03-01
2018-09-30
Brief Summary
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Detailed Description
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Introduction: goitre is endemic in Sudan with prevalence ranging between 5-42% in different regions of the country. Patients are referred for surgery only if they develop pressure symptoms.
The incidence of thyroid carcinoma is high in endemic goitrous areas. Determining the risk of cancer in patient with long standing goitres may help in early early referral and early surgical intervention.
Methods: This is prospective cohort study including 160 patients with long standing goitrers of 10 years or more who presented from March 2017 to September 2017 to Khartoum Teaching Hospital-Sudan
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Patients with goitres 10 years or more
Patients with long standing multinodular goitres of 10years or more presenting to surgical unit in Khartoum Teaching Hospital -Sudan. Checking incidence of malignancy in this group.
Histopathology
Thyroidectomy for patients and histological examination of specimen to determine incidence of malignancy.
Interventions
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Histopathology
Thyroidectomy for patients and histological examination of specimen to determine incidence of malignancy.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Sudan Medical Specialization Board
OTHER_GOV
University of Khartoum
OTHER
Responsible Party
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Seifeldin Mahdi
Associate professor of surgery
Principal Investigators
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Mohamed Elmakki Abdella, MS,FRCSI
Role: STUDY_DIRECTOR
University of Khartoum -Faculty of Medicine
Locations
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Faculty of Medicine University of Khartoum
Khartoum, , Sudan
Countries
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Other Identifiers
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UofK
Identifier Type: -
Identifier Source: org_study_id
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