Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer

NCT ID: NCT01074684

Last Updated: 2023-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

959 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2021-12-01

Brief Summary

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The purpose of this study is to describe the correlation between the cytohistology exam of patients undergoing thyroid surgery, and the predictive values of: suspicious clinical findings, preoperative thyroid imaging, and the incidence of thyroid cancer in cytologically negative nodes.

Detailed Description

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Conditions

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Thyroid Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Consecutive patients presenting for thyroid disease (palpable nodules)
* Indication for surgery
* Age \> 18 years
* Signed informed consent for surgery
* Signed informed consent for data collection

Exclusion Criteria

* Concurrent condition that contraindicates surgery
* Clinical or radiologic evidence of locally advanced tumor
* Clinical or radiologic evidence of metastatic lymph nodes or distant metastases
* Nonpalpable nodes
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute, Naples

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Luciano Pezzulo, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Cancer Institute, Naples

Maria Grazia Chiofalo, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Cancer Institute, Naples

Massimo Di Maio, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Cancer Institute, Naples

Francesco Perrone, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

National Cancer Institute, Naples

Locations

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Università di Cagliari

Cagliari, , Italy

Site Status

Azienda Ospedaliera Unviersitaria Careggi - Firenze

Florence, , Italy

Site Status

ASL TO/4 Ospedale di Ivrea

Ivrea, , Italy

Site Status

Istituto Nazionale dei Tumori

Napoli, , Italy

Site Status

Azienda Ospedaliera Universitaria di Padova

Padua, , Italy

Site Status

Università Cattolica del Sacro Cuore di Roma Policlinico Gemelli

Roma, , Italy

Site Status

Ospedale di Taormina

Taormina, , Italy

Site Status

Università degli studi di Perugia - Sede di Terni

Terni, , Italy

Site Status

Countries

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Italy

Other Identifiers

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TIR-2009-01

Identifier Type: -

Identifier Source: org_study_id

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