Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

NCT ID: NCT00571090

Last Updated: 2014-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

735 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-06-30

Study Completion Date

2013-07-31

Brief Summary

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The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.

Detailed Description

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Conditions

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Thyroid Nodule

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Thyroid nodule

Subjects who present with thyroid nodules will be enrolled into the study. Euthyroid and hypothyroid subjects with a solitary thyroid nodule or multinodular goiter will be enrolled. For subjects with a suppressed TSH, a thyroid scan will be performed. Subjects with a hypoactive nodule in the thyroid scan and a low TSH will be enrolled.

Thyroid ultrasonography

Intervention Type PROCEDURE

Ultrasound-guided thyroid fine-needle aspiration biopsy

Interventions

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Thyroid ultrasonography

Ultrasound-guided thyroid fine-needle aspiration biopsy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Subjects with thyroid nodules over 10 mm in the longest diameter
* Euthyroid or hypothyroid subjects with a solitary thyroid nodule or multinodular goiter
* Subjects with a hypoactive nodule in the thyroid scan and a low TSH

Exclusion Criteria

* Subjects with four or more thyroid nodules that are over 10 mm
* Subjects with low TSH and hyperactive nodule on thyroid scan
Minimum Eligible Age

15 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Group Florence Nightingale

OTHER

Sponsor Role collaborator

Istanbul Science University

OTHER

Sponsor Role lead

Responsible Party

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Ahmet Selcuk Can

Associate Professor of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmet Selcuk Can, MD

Role: PRINCIPAL_INVESTIGATOR

Istanbul Science University and Group Florence Nightingale

Locations

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Group Florence Nightingale

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Can AS. Cost-effectiveness comparison between palpation- and ultrasound-guided thyroid fine-needle aspiration biopsies. BMC Endocr Disord. 2009 May 16;9:14. doi: 10.1186/1472-6823-9-14.

Reference Type BACKGROUND
PMID: 19445710 (View on PubMed)

Related Links

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http://www.biomedcentral.com/1472-6823/9/14

Free research article from the data of this protocol

Other Identifiers

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511

Identifier Type: OTHER

Identifier Source: secondary_id

B.30.2.IBU.0.01.00.00/511

Identifier Type: -

Identifier Source: org_study_id

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