Improved Preoperative Selection of Cold Thyroid Nodules

NCT ID: NCT00297297

Last Updated: 2010-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-12-31

Study Completion Date

2011-03-31

Brief Summary

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Molecular gene profiling of fine-needle aspiration samples in addition to fine-needle aspiration cytology can improve the selection of patients with benign versus malignant thyroid nodules with improved sensitivity.

Detailed Description

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Conditions

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Thyroid Nodules

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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No intervention. Applying gene profiling on needle aspirates

Intervention Type OTHER

Other Intervention Names

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Genetics - molecular profiling of tissue samples

Eligibility Criteria

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Inclusion Criteria

* Solitary thyroid nodules that appear solid on ultrasound and cold on a scintiscan

Exclusion Criteria

* Pregnancy and lactation
* Age below 20 years
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Herlev Hospital

OTHER

Sponsor Role lead

Responsible Party

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Herlev University Hospital

Principal Investigators

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Finn N Bennedbaek, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Endocrinology and Metabolism, Herlev University Hospital, DK-2730 Herlev, Denmark

Locations

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Outpatient clinic of The Department of Endocrinology, Herlev University Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Finley DJ, Zhu B, Barden CB, Fahey TJ 3rd. Discrimination of benign and malignant thyroid nodules by molecular profiling. Ann Surg. 2004 Sep;240(3):425-36; discussion 436-7. doi: 10.1097/01.sla.0000137128.64978.bc.

Reference Type RESULT
PMID: 15319714 (View on PubMed)

Other Identifiers

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HH-FB-10

Identifier Type: -

Identifier Source: org_study_id

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