HIIT on Overweight Middle-aged Adults

NCT ID: NCT06383442

Last Updated: 2024-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-25

Study Completion Date

2023-11-22

Brief Summary

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36 middle-aged with overweight adults were divided into three groups: 1. L-HIIT group: the long-interval HIIT group (4 × 4 min Exercise/4 min Rest), 2. M-HIIT group: the medium-interval HIIT group (8 × 2 min Exercise/2 min Rest), 3. Control group: no exercise intervention. All groups carried out the training stage for 8 weeks (three sessions per week) and the detraining stage for 4 weeks in order to investigate the effects induced by different HIIT interventions on inflammation, metabolic adaptation, anti-fatigue and exercise performance, and fat loss.

Detailed Description

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Aging, obesity, have been shown to lead to higher oxidative stress and chronic inflammation. However, high-intensity interval training (HIIT) has anti-inflammatory and anti-obesity benefits. Different training prescriptions may also affect improvements. Therefore, this study will explore the optimal HIIT prescription to improve fat, inflammation, metabolism, and exercise performance in overweight middle-aged and older adults. Thirty-six middle-aged with overweight adults were divided into three groups: 1. L-HIIT group: the long-interval HIIT group (4 × 4 min Exercise/4 min Rest), 2. M-HIIT group: the medium-interval HIIT group (8 × 2 min Exercise/2 min Rest), 3. Control group: no exercise intervention. All groups carried out the training stage for 8 weeks (three sessions per week), then the detraining stage for 4 weeks in order to investigate the effects induced by different HIIT interventions on inflammation, metabolic adaptation, anti-fatigue and exercise performance, and fat loss.

Conditions

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Overweight or Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants were evenly distributed according to a counterbalanced design and divided into three different groups by the body fat percentage of subjects: 1. L-HIIT group: the long-interval HIIT group (4 × 4 min Exercise/4 min Rest), 2. M-HIIT group: the medium-interval HIIT group (8 × 2 min Exercise /2 min Rest), 3. Control group. Target intensities of each interval bout, exercise and rest (Ex./R.), were 85-90% VO2peak/65-70% VO2peak zones, respectively.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Control group

Group Type NO_INTERVENTION

No interventions assigned to this group

M-HIIT

Group Type EXPERIMENTAL

M-HIIT

Intervention Type OTHER

the medium-interval HIIT group (8 × 2 min Exercise /2 min Rest)

L-HIIT

Group Type EXPERIMENTAL

L-HIIT

Intervention Type OTHER

the long-interval HIIT group (4 × 4 min Exercise/4 min Rest)

Interventions

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L-HIIT

the long-interval HIIT group (4 × 4 min Exercise/4 min Rest)

Intervention Type OTHER

M-HIIT

the medium-interval HIIT group (8 × 2 min Exercise /2 min Rest)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Recruit people who are overweight or obese (BMI between 24-35) who are 20-65 years old and have no exercise habits in a sitting lifestyle.

Exclusion Criteria

* If there are any of the following circumstances, they are not allowed to participate in this research and are included in the listing conditions of this case:

1. Have smoking and drinking habits.
2. People who have stroke, type 1 and type 2 diabetes, neuromuscular disease, so that they cannot participate in physical activities.
3. Chronic obstructive lung disease, asthma, interstitial lung disease or alveolar cyst fibrosis.
4. Metabolic diseases include thyroid disease, kidney disease (kidney, bladder stones) or liver disease.
5. Those with arrhythmia, a rhythm regulator, severe cardiovascular disease, peripheral vascular disease or cerebrovascular disease.
6. People with epilepsy and rheumatoid arthritis.
7. Those who have implanted artificial joints in the past six months and have had recent surgery.
8. Migraine, acute thrombosis and hernia.
9. Those who have engaged in strenuous exercise or have muscle aches within 24 hours before the experiment.
10. People who feel unwell due to other reasons during the experiment.
11. People with severe food allergies.
12. Have hospitalization records within three months.
13. People with cognitive impairment.
14. Take any drugs that affect the function of the nervous system.
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Taipei Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Taipei Medical University

Taipei, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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N202103041

Identifier Type: -

Identifier Source: org_study_id

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