The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

NCT ID: NCT06382376

Last Updated: 2024-04-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

71 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2024-03-01

Brief Summary

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The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.

The key question(s) it aims to answer are:

\[Is intrathecal morphine more effective in postoperative analgesia?\] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.

Detailed Description

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Our study was designed retrospectively. The investigators evaluated analgesia methods in patients who underwent laparoscopic or open surgery due to gynecological cancer between June 2023 and December 2023. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block on postoperative analgesia and opioid use.

Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group

Conditions

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Gynecological Cancer Surgery Regional Anesthesia Morbidity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group 1: Intrathecal morphine administered group

Group 1: Intrathecal morphine administered group

Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group

Intervention Type PROCEDURE

Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group

Group 2: Four quadrant transversus abdominis plane block applied group

Group 2: Four quadrant transversus abdominis plane block applied group

Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group

Intervention Type PROCEDURE

Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group

Interventions

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Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group

Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group

Intervention Type PROCEDURE

Other Intervention Names

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Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group

Eligibility Criteria

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Inclusion Criteria

* 18 years

* Patients who have undergone gynecological cancer surgery

Exclusion Criteria

* \<18 years
* Those with missing data
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Bakirkoy Dr. Sadi Konuk Research and Training Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Duygu Akyol

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Duygu Akyol

Role: PRINCIPAL_INVESTIGATOR

Başakşehir Çam & Sakura City Hospital

Locations

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Başakşehir Çam and Sakura City Hospital

Istanbul, Basaksehir, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Black KA, Nelson G, Goucher N, Foley J, Pin S, Chong M, Ghosh S, Bisch SP. Effect of transversus abdominis plane block on postoperative outcomes in gynecologic oncology patients managed on an Enhanced Recovery After Surgery pathway. Gynecol Oncol. 2023 Nov;178:1-7. doi: 10.1016/j.ygyno.2023.09.003. Epub 2023 Sep 18.

Reference Type RESULT
PMID: 37729808 (View on PubMed)

Niraj G, Kelkar A, Hart E, Kaushik V, Fleet D, Jameson J. Four quadrant transversus abdominis plane block and continuous transversus abdominis plane analgesia: a 3-year prospective audit in 124 patients. J Clin Anesth. 2015 Nov;27(7):579-84. doi: 10.1016/j.jclinane.2015.07.005. Epub 2015 Aug 28.

Reference Type RESULT
PMID: 26319886 (View on PubMed)

Pirie K, Traer E, Finniss D, Myles PS, Riedel B. Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions. Br J Anaesth. 2022 Sep;129(3):378-393. doi: 10.1016/j.bja.2022.05.029. Epub 2022 Jul 6.

Reference Type RESULT
PMID: 35803751 (View on PubMed)

Meylan N, Elia N, Lysakowski C, Tramer MR. Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials. Br J Anaesth. 2009 Feb;102(2):156-67. doi: 10.1093/bja/aen368.

Reference Type RESULT
PMID: 19151046 (View on PubMed)

Other Identifiers

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2024-60

Identifier Type: -

Identifier Source: org_study_id

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