Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Surgery
NCT ID: NCT07312825
Last Updated: 2025-12-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
94 participants
OBSERVATIONAL
2024-01-01
2025-03-20
Brief Summary
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The main question is whether the combination of TAP block with Quadratus Lumborum Block (QLB) or Rectus Sheath Block (RSB) provides superior pain relief compared to TAP block alone.
All blocks were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's judgment. No randomization, allocation, or study-directed intervention was performed.
Patients were classified into three groups based on the block type they received during standard care:
Group 1: TAP Block Only
Group 2: TAP + QLB Combination
Group 3: TAP + RSB Combination
Postoperative data, including pain scores (VAS), opioid consumption, sedation level, heart rate, blood pressure, nausea/vomiting, and length of hospital stay, were collected prospectively.
The study aims to determine which block combination provides the best postoperative pain control and recovery profile in patients undergoing gynecologic oncology surgery.
Detailed Description
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All blocks (Transversus Abdominis Plane \[TAP\] block, Quadratus Lumborum Block \[QLB\], and Rectus Sheath Block \[RSB\]) were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's preference.
No intervention, randomization, or protocol-directed procedure was applied for research purposes. After data collection, patients were classified into three groups based on the block type they had received in standard care:
TAP block only
TAP + QLB combination
TAP + RSB combination
The study prospectively compared postoperative pain scores (VAS), opioid consumption, time to mobilization, bowel function recovery, and length of hospital stay among these groups to determine the most effective analgesic strategy within routine practice.
This observational design reflects real-world anesthesia management and does not involve any experimental or interventional component.
Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Group 1: TAP Block Only Group
Patients who received only Transversus Abdominis Plane (TAP) block as part of routine anesthesia practice. No additional regional block was performed.
Group 1:The Transversus Abdominis Plane (TAP) block
Patients who received only Transversus Abdominis Plane (TAP) block as part of routine clinical anesthesia practice. No study-assigned intervention or randomization was performed. Data were collected prospectively from standard anesthesia records.
Group 2: TAP + QLB Combination
Patients who received both TAP block and Quadratus Lumborum Block (QLB) as part of standard clinical anesthesia management.
Group 2: TAP Block + Quadratus Lumborum Block (QLB)
Patients who received TAP block combined with Quadratus Lumborum Block (QLB) during routine anesthesia management. This block combination was chosen by the attending anesthesiologist as part of standard care, not assigned by the study.
Group 3: TAP + RSB Combination
Patients who received both TAP block and Rectus Sheath Block (RSB) as part of standard clinical anesthesia management.
Group 3: TAP Block + Rectus Sheath Block (RSB)
Patients who received TAP block combined with Rectus Sheath Block (RSB) as part of routine anesthesia practice. The block technique was performed according to clinical judgment, not as part of a study intervention.
Interventions
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Group 1:The Transversus Abdominis Plane (TAP) block
Patients who received only Transversus Abdominis Plane (TAP) block as part of routine clinical anesthesia practice. No study-assigned intervention or randomization was performed. Data were collected prospectively from standard anesthesia records.
Group 2: TAP Block + Quadratus Lumborum Block (QLB)
Patients who received TAP block combined with Quadratus Lumborum Block (QLB) during routine anesthesia management. This block combination was chosen by the attending anesthesiologist as part of standard care, not assigned by the study.
Group 3: TAP Block + Rectus Sheath Block (RSB)
Patients who received TAP block combined with Rectus Sheath Block (RSB) as part of routine anesthesia practice. The block technique was performed according to clinical judgment, not as part of a study intervention.
Eligibility Criteria
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Inclusion Criteria
* ASA physical status I-IV.
* Scheduled for major gynecologic oncology surgery (endometrial cancer, ovarian tumor, or cytoreductive surgery).
* Undergoing general anesthesia.
* Planned postoperative abdominal fascial plane block for pain management (TAP, TAP + QLB, or TAP + RSB).
* Able to provide written informed consent.
Exclusion Criteria
* Emergency surgery.
* Known allergy or contraindication to local anesthetics.
* Infection at the block site.
* Coagulopathy or anticoagulant use that contraindicates regional anesthesia.
* Pre-existing chronic pain conditions or chronic opioid use.
* Severe hepatic or renal insufficiency.
* Cognitive impairment that prevents reliable pain assessment.
18 Years
FEMALE
No
Sponsors
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Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
OTHER
Responsible Party
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Ayşe Menekşe Çakır
Doctor of Anesthesiology
Locations
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Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Ankara, , Turkey (Türkiye)
Countries
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References
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Yu S, Wen Y, Lin J, Yang J, He Y, Zuo Y. Combined rectus sheath block with transverse abdominis plane block by one puncture for analgesia after laparoscopic upper abdominal surgery: a randomized controlled prospective study. BMC Anesthesiol. 2024 Feb 9;24(1):58. doi: 10.1186/s12871-024-02444-6.
Zhu JL, Wang XT, Gong J, Sun HB, Zhao XQ, Gao W. The combination of transversus abdominis plane block and rectus sheath block reduced postoperative pain after splenectomy: a randomized trial. BMC Anesthesiol. 2020 Jan 23;20(1):22. doi: 10.1186/s12871-020-0941-1.
Akerman M, Pejcic N, Velickovic I. A Review of the Quadratus Lumborum Block and ERAS. Front Med (Lausanne). 2018 Feb 26;5:44. doi: 10.3389/fmed.2018.00044. eCollection 2018.
Other Identifiers
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FASIALBLOCKJinekoOnkoAnj
Identifier Type: -
Identifier Source: org_study_id