Effects Of Quadratus Lumborum Type 1 Block And Transversalis Facial Plane Block On Acute Pain In Gynecological Surgery

NCT ID: NCT07114965

Last Updated: 2025-08-11

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 68 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-06-01
• Study Completion Date: 2025-08-01

Brief Summary

This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Transversalis Fascial Plane blocks on postoperative acute pain in gynecology operations.

Detailed Description

In gynecological operations, especially total abdominal hysterectomy, moderate to severe postoperative pain is usually accompanied. Inadequately treated postoperative abdominal hysterectomy pain causes delayed postoperative recovery, prolonged hospital stay, chronic pain, increased chance of venous thrombosis and patient dissatisfaction. Multimodal analgesia techniques are widely used, but new evidence has shown that combinations with regional anesthesia techniques are the most effective method in postoperative pain treatment. Opioids continue to be the main step in postoperative pain treatment, despite strong evidence of their disadvantages. Opioid administration in acute postoperative pain is associated with many side effects such as sedation, pruritus, nausea and vomiting. Regional analgesia techniques used to reduce the amount of opioid used and provide effective analgesia are becoming an integral part of postoperative opioid-sparing analgesia. Open surgeries increase tissue trauma and increase inflammatory response due to high surgical stress. The reduction of pain by regional analgesia application facilitates postoperative mobilization and reduces complications. Abdominal wall blocks are performed on the principle of high-volume local anesthetic deposition within a fascial plane. Ultrasound-guided performance with continuous visualization of the needle improves placement accuracy and reduces inadvertent visceral or neurovascular injury. Abdominal wall blocks primarily provide somatic analgesia, but newer blocks can also block visceral nerves. Abdominal wall blocks provide a relatively safe alternative to epidural analgesia without the risk of motor block, hypotension, or central neuraxis. The quadratus lumborum fascial block (QLB), recently described by Blanco and modified by Sauter et al, is considered an extension of the TAP block. A local anesthetic is injected adjacent to the QL muscle, which aims to anesthetize the thoracolumbar nerves. The QL muscle is a quadrangular-shaped posterior abdominal wall muscle that inserts inferiorly on the iliac crest, cranially on the 12th rib, medially on the transverse processes of L1 to L4, and has a free lateral margin. The QL muscle is related to the PM muscle on its anterior surface and to the spinal erector muscle group on its posterior surface. The muscle is surrounded by the thoracolumbar fascia. Three techniques for QLB have been described and named according to the position of the needle tip in relation to the QL muscle: QLB type 1 or lateral; type 2 or posterior; and transmuscular, or anterior. Many case reports and randomized trials have included analgesia for gynecologic and lower abdominal surgery, Pfannenstiel incision for cesarean section, proctosigmoidectomy, hip surgery, abdominal hernioplasty, nephrectomy, and laparotomy as indications. There are several case reports with different indications for QLB for sensory block between T7 and L2. The transversalis fascial plane block is a truncal block that targets the L1 nerve branches, namely the ilioinguinal and iliohypogastric nerves. The ilioinguinal and iliohypogastric nerves originate from the lateral border of the psoas major muscle, below the 12th rib, and run along the anterior surface of the quadratus lumborum muscle. Lateral to the quadratus lumborum muscle, it initially descends deep to the transversus abdominis muscle for a variable distance and penetrates the transversus abdominis muscle to enter the transversus abdominis plane between the internal oblique and transversus abdominis muscles. This block is also an analgesic option for inguinal hernia repair, open appendectomy, and any surgical procedure involving the L1 dermatome. In this study, the investigators will evaluate the effectiveness of quadratus lumborum and transversalis fascial plane blocks, which are abdominal wall blocks, on postoperative acute pain in open gynecological operations.

Conditions

Postoperative Pain; Gynecologic Surgery

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

open gynecological operations

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• ASA I-III
• 18-80 years old women's medicines
• Open myomectomy and total abdominal hysterectomy cases

Exclusion Criteria

• Those who do not want a block
• Patients who are allergic to local anesthetics
• Patients with coagulopathy ·
• Pregnancy
• Previous surgery in the area where the block will be applied

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Ankara Diskapi Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

ilkay baran akkuş

specialist doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Ankara Etlik City Hospital

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

AEŞH-EK-2025-151

Identifier Type: -

Identifier Source: org_study_id