Postoperative New-onset Proteinuria and Adverse Outcomes.

NCT ID: NCT06339229

Last Updated: 2024-04-01

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2983899 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2000-01-01
• Study Completion Date: 2023-11-01

Brief Summary

We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery. The exposure variable was the dipstick proteinuria values from the initial postoperative urinalysis within 30 days after surgery, categorized as negative, trace, 1+, and ≥2+. The primary outcome was 30-day mortality. The secondary outcomes included 1-year mortality and composite kidney outcome assessed using the postoperative estimated glomerular filtration rate.

Conditions

Surgery; Proteinuria; Mortality

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

surgery patients

proteinuria

Intervention Type: OTHER

dipstick proteinuria values negative, trace, 1+, and ≥2+

Interventions

proteinuria

dipstick proteinuria values negative, trace, 1+, and ≥2+

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• surgery patients

Exclusion Criteria

• kidney or urinary surgery
• missing urinalysis results
• dipstick proteinuria indicated a value of "≥ trace" at least once preoperatively
• with dialysis, end-stage renal disease, or with urinary tract infection at baseline
• missing follow-up information

• Minimum Eligible Age: 16 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Yaozhong Kong

OTHER

Sponsor Role: lead

Responsible Party

Yaozhong Kong

Professor

Responsibility Role: SPONSOR_INVESTIGATOR

Other Identifiers

FSYYY-2024-12

Identifier Type: -

Identifier Source: org_study_id