Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

NCT ID: NCT06462755

Last Updated: 2024-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

57089 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-01

Study Completion Date

2018-12-31

Brief Summary

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To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population.

The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation.

Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

Detailed Description

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Conditions

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Postoperative Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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elderly patients (aged ≥ 65 years)

elderly patients undergo surgeries

No intervention

Intervention Type OTHER

no intervention

Interventions

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No intervention

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries

Exclusion Criteria

* (1) Patients who underwent endoscopic or transplant procedures;
* (2) Patients who underwent surgeries lasting longer than 10 hours;
* (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) \< 15 ml/min per 1.73 m2;
* (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.
Minimum Eligible Age

65 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Weidong Mi

Director (Cheif expert of National key research and development program of China 2018YFC2001900)

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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PLAGH-AOC-R01

Identifier Type: -

Identifier Source: org_study_id

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