Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate
NCT ID: NCT06313216
Last Updated: 2025-11-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
63 participants
INTERVENTIONAL
2024-03-15
2025-11-15
Brief Summary
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The present study included 63 patients, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation with Duo-Teck membrane, while group II patients underwent the same procedure, but the dehisced bone defect was grafted by autogenous demineralized tooth graft. finally group III was grafted by combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate.
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Detailed Description
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One of the various indications of implant therapy is the replacement of periodontally hopeless teeth. The successful use of dental implants for more than 3 decades has been extensively documented for both conventional and immediate implant therapy.
The installation of implants in extraction sockets was advocated as a means to reduce the number of surgical procedures; to preserve the dimensions of the alveolar ridge; to reduce the interval between the removal of the tooth and the insertion of the implant supported restoration and furthermore, it may enhance osseointegration by taking advantage of the natural bone healing process around the implant.
A variety of regenerative techniques using combinations of bone grafts and barrier membranes have been suggested to promote bone regeneration in localized defects at implants placed into extraction sockets (Mayfield 1999). Bone substitutes were used to fill the marginal void between the implant and the bone, and barrier membranes were placed to protect the site during healing.
In the presence of fenestration or dehiscence defects, the potential for spontaneous bone formation at such defects is poor, so it is advised to use augmentation procedures for bone enhancement. Bone augmentation procedures are effective in promoting bone fill and defect resolution at implants placed in post-extraction sites, and are more successful with immediate and immediate-delayed placement than with conventional delayed placement.
The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate and compared this approach to autogenous demineralized tooth graft.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Immediate Implant Placement Using duoteck membrane
after insertion of immediate implant, the dehisced bone defect will be grafted Using duoteck membrane
duoteck membrane
the dehisced bone defect will be covered with duoteck membrane
Immediate Implant Placement autogenous demineralized tooth graft
after insertion of immediate implant, the dehisced bone defect will be grafted Using autogenous demineralized tooth graft
autogenous demineralized tooth graft
the dehisced bone defect will be covered with autogenous demineralized tooth graft
Immediate Implant Placement with autogenous demineralized tooth graft and tooth plate
after insertion of immediate implant, the dehisced bone defect will be grafted Using autogenous demineralized tooth graft and autogenous demineralized tooth plate
autogenous demineralized tooth graft and plate
the dehisced bone defect will be covered with autogenous demineralized tooth graft combined with autogenous demineralized tooth plate
Interventions
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duoteck membrane
the dehisced bone defect will be covered with duoteck membrane
autogenous demineralized tooth graft
the dehisced bone defect will be covered with autogenous demineralized tooth graft
autogenous demineralized tooth graft and plate
the dehisced bone defect will be covered with autogenous demineralized tooth graft combined with autogenous demineralized tooth plate
Eligibility Criteria
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Inclusion Criteria
* presence of non-restorable maxillary anterior tooth
* had intact socket walls following tooth extraction
* the gingival biotype was thick.
Exclusion Criteria
* history of using bisphosphonates or other drugs that might impact bone turnover
* a history of smoking during the previous five years,
* a history of any acute infections at the surgical site,
* teeth having root resorptions
20 Years
40 Years
ALL
Yes
Sponsors
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Kafrelsheikh University
OTHER
Responsible Party
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Walid Elamrousy
Assistant Professor of periodontology
Principal Investigators
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Walid AH Elamrousy, PhD
Role: PRINCIPAL_INVESTIGATOR
Faculty of Oral and Dental Medicine, Kafrelsheikh University
Locations
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faculty of dentistry, kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, Egypt
Countries
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Other Identifiers
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KFSIRB200-187
Identifier Type: -
Identifier Source: org_study_id
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