Influence of Human Platelet Derivatives on Dental Implant
NCT ID: NCT06044246
Last Updated: 2024-03-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
30 participants
INTERVENTIONAL
2024-06-20
2025-07-30
Brief Summary
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Aims of the study:
* To study the effect of PRF membrane (with or without bone substitute on increasing bone dimension around dental implant.
* To investigate the effects of compositions of PRF (platelets count, WBC count) on bone healing.
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Detailed Description
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PRF will be obtained from a blood sample that is taken from the patient at the time of surgery in 10-mL tubes, the blood-containing tube is placed in a centrifuge at specially controlled rotations, temperature and time. The result is the separation of blood, basically from two by-products, including PRF. The PRF clot will be placed in specific box ( P.R.F -System; Surgident, CE ) to create a PRF membrane with specific thickness that will be placed on the bone around dental implant.
Evaluation of the results
* Alveolar bone width around dental implant will be measured.
* Histological examination of the tissue that excised during dental implant uncover surgery.
* Evaluate pain by visual analogue score (VAS).
* Estimate the count of WBC and platelets in whole blood will be obtained from a laboratory results.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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experimental group
Placing dental implant with PRF membrane treatment alone or combined with bone substitute.
PRF membrane
Placing implant with PRF membrane treatment
control group
Placing dental implant
No interventions assigned to this group
Interventions
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PRF membrane
Placing implant with PRF membrane treatment
Eligibility Criteria
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Inclusion Criteria
* No medical history of any systemic diseases that affect the bone metabolism.
* Did not receive any systemic drugs.
* Has edentulous area that needs dental implant.
Exclusion Criteria
* Pathology in the edentulous region.
* Bruxism.
* Disease of the oral mucosa.
20 Years
ALL
Yes
Sponsors
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Al-Mustansiriyah University
OTHER
Responsible Party
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Afya Sahib Diab Al-radha
Assistant Professor
Principal Investigators
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Assis. Prof. Dr. Afya SD Al-radha
Role: PRINCIPAL_INVESTIGATOR
College of Dentistry, Mustansiriyah University.
Locations
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Kadhimiya Teaching HospitalKadhimiya Educational Hospital
Baghdad, Alkadhmiya City, Iraq
Countries
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Central Contacts
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Provided Documents
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Document Type: Informed Consent Form
Other Identifiers
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MUOSU-202103
Identifier Type: -
Identifier Source: org_study_id
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