Goat or Cow Milk Based Infant Formula GMS

NCT ID: NCT06312059

Last Updated: 2024-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE2/PHASE3

Total Enrollment

264 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-14

Study Completion Date

2024-08-15

Brief Summary

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This study is a non-inferiority, decentralized, randomized, double-blind, controlled clinical trial evaluating the growth, tolerance, and safety of a goat's-milk test infant formula (Test Formula 1; TF1) and a cow's-milk test infant formula (Test Formula 2; TF2), each compared to a cow's-milk infant formula commercially available in the United States (Control Formula; CF).

Detailed Description

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Conditions

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Growth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
RP Over stickered TP in blank packaging.

Study Groups

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Market leader- Competitor Cow Milk based infant formula

Intervention with Competitor product currently in market- Control.

Group Type ACTIVE_COMPARATOR

Advance Infant Formula Powder

Intervention Type OTHER

Sole source infant nutrition for the control arm.

Test product Cow Milk based infant formula

Intervention with Test product product - Test arm.

Group Type EXPERIMENTAL

"Kendamil Cow milk test product

Intervention Type OTHER

Sole source infant nutrition for the cow milk test arm.

Test product Goat Milk based infant formula

Intervention with Test product product - Test arm.

Group Type EXPERIMENTAL

"Kendamil goat milk test product

Intervention Type OTHER

Sole source infant nutrition for the goat milk test arm.

Interventions

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Advance Infant Formula Powder

Sole source infant nutrition for the control arm.

Intervention Type OTHER

"Kendamil Cow milk test product

Sole source infant nutrition for the cow milk test arm.

Intervention Type OTHER

"Kendamil goat milk test product

Sole source infant nutrition for the goat milk test arm.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Healthy term infants (37 to 42 weeks gestation at birth) from a singleton birth as assessed by the investigator
2. Infants with a birth weight of \>2500 g to \<4500 g
3. Infants ≤11 days of age at enrollment; birth constitutes Day 0
4. Parent/legal guardian who has previously decided to exclusively feed infant formula and is willing to continue with formula feeding throughout the study

Exclusion Criteria

A participant who meets any of the following criteria will be excluded from participation in the study:

1. Infant born with medical complications (e.g., neurological, cerebral palsy, etc.)
2. Infant with failure to thrive, fever, any GI tract abnormalities (e.g., short gut, gastroesophageal reflux, etc.), any congenital illness or malformation that may affect infant feeding or normal growth
3. Infant has been treated with prescription medications that in the Investigator's opinion could impact growth, gastrointestinal tolerance and/or development
4. Infant that has received oral or parenteral antibiotics prior to enrollment
5. Infant is taking and parent/legal guardian plans to continue (including over-the-counter medications, such as Mylicon® for gas), home remedies (such as juice for constipation), gastroesophageal reflux medications, herbal preparations, or rehydration fluids that, in the Investigator's opinion, might affect gastrointestinal tolerance. Use of the following are strongly discouraged for the duration of the trial:

1. Solid foods and juices
2. Vitamins and/mineral supplements, as the study product provided is nutritionally complete
3. Pre- and probiotics
6. Infant with family history (biological siblings or parents) of confirmed milk protein allergy (Parent's lactose intolerance is not disqualifying)
7. Parent(s)/Legal guardian(s) intent on feeding non-study formula, breastmilk, juices, or solid food during the study.
Maximum Eligible Age

14 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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ObvioHealth

INDUSTRY

Sponsor Role collaborator

Kendal Nutricare Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Allan Soo

Role: PRINCIPAL_INVESTIGATOR

MD, FAPCR ObvioHealth USA, Inc.

Locations

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ObvioHealth USA, Inc.

New York, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Luke Douglas

Role: CONTACT

+44 (0)7950211990

Will McMahon

Role: CONTACT

+44( 0)7484056316

Facility Contacts

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Parth Shah

Role: primary

513-571-5377

Other Identifiers

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KNC-GMS-002

Identifier Type: -

Identifier Source: org_study_id

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